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Exam (elaborations)

BSN 315 Pharm II Week 12 Antivirals Exam

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Antiviral and Antiretroviral Therapy Oseltamivir is approved for the prevention and treatment of influenza in persons 1 year and older. The drug inhibits viral replication and shortens duration of influenza. It should be started within 48 hours of influenza symptoms. Patient Safety Hydration is important while taking oseltamivir. - ans-Acyclovir is a synthetic purine nucleoside analog and is the drug of choice to treat infections caused by members of the herpesvirus family. Acyclovir inhibits viral DNA synthesis. It also inhibits the activity of HSV-1 HSV-2, and varicella zoster. Acyclovir is used to treat encephalitis, herpes genitalis and labialis, herpes zoster, varicella, and complicated infection with herpes simplex virus. Ribavirin is an antiviral which is active against many DNA and RNA viruses. It is effective in treating RSV and chronic HCV (hepatitis C). Ribavirin sequestered in erythrocytes remains in the system for weeks. - ans-Lamivudine is effective against chronic HBV. The goals of pharmacologic treatment of hepatitis with antivirals are to reduce or suppress liver inflammation, thereby decreasing the progression to cirrhosis and its complications. Lamivudine inhibits reverse transcriptase, which prevents virus cells from replicating. Question 1 of 4 Which statement is accurate with respect to the goal of antiviral treatment for viral hepatitis B (HBV)? To reduce or suppress liver inflammation To kill all HBV To enhance the patient's immune system

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