GMS 6401 Mock Exam Questions and Answers Already Passed

GMS 6401 Mock Exam Questions and Answers Already Passed The kidney consists of specialized vascular and tubular structures (the nephron) which collaborate in the production of urine: The glomerular capillary is surrounded by an epithelial structure which forms the beginning of the tubule. A diagnostic renal clearance experiment is conducted and the following steady state (= equilibrium) measurements are obtained on a 34 year old male subject, weighing 60 kg (assume that the renal plasma flow (RPF) is the same as the effective renal plasma flow (ERPF): Urine inulin = 200 mg/100ml Plasma inulin = 4 mg/100ml Urine flow (V) = 2ml/min Urine PAH = 1200 mg/100ml Plasma PAH = 6 mg/100ml GFR = 100ml/min Any substance which is freely filtered at the glomerulus, is reabsorbed and is not secreted, will have a renal clearance that is: Choose one best answer. Less than the clearance of inulin An increased protein excretion (proteinuria) can indicate glomerular damage. Which of the following changes are likely to cause proteinuria? Choose 1 best answer: Loss of nephrin from the epithelial slit pore diaphragm Maintenance of a high glomerular filtration rate (GFR) is required for optimal kidney function. Which of the following options would be most likely to associate with a below optimal GFR in man? A low glomerular capillary water permeability A selective increase in renal plasma flow (RPF) due to parallel relaxation of theafferent and efferent arterioles leads to: (Choose one best answer.) A rise in GFR with no change in filtration fraction An increase in renal blood flow will lead to which of the following changes within the kidney: (Choose one best answer.) Increased total renal oxygen consumption but little change in the renal venous oxygen content (arterial - venous difference) In which tubule segment is there active sodium reabsorption by the Na/K/2Cl (NKCC2) transporter but never any water reabsorption? Thick ascending limb of the loop of Henle The release of renin from the kidney, into the circulation is stimulated by: A fall in renal perfusion pressure An extracellular fluid volume expansion leads to: Increased right atrial pressure A reduction in sodium excretion occurs when: Septic shock occurs An increased in renal sympathetic nerve activity will lead to which combination of changes: Increased renal renin release and a