UNE Medical Biochem Final Exam Review Questions With 100% Correct Answers

UNE Medical Biochem Final Exam Review Questions With 100% Correct Answers short chain fatty acids and medium chain fatty acids enter mitochondria by: - answerDiffusion Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will activate which of the following enzymes? - answerHormone sensitive lipase the process of ketogenesis refers to the conversion of acetyl-CoA to which of the following compounds? - answerB-hydroxybutyrate A well, 2-year-old female presents to the clinic with symptoms of a viral illness. She had vomiting and diarrhea, weak, hypoglycemic, elevated liver enzymes, NO KETONES in urine. Laboratory analysis shows elevated medium chain fatty acylcarnitines in blood....which abnormality is the likely diagnosis for the child? - answerDefect of medium chain coenzyme A dehydrogenase Ketonuria, hyperglycemia and severe acidosis are diagnostic indicators of the presentation of type 1 diabetic ketoacidosis. Which of the following compounds are ketone bodies that would be elevated in serum and urine from a patient in this condition? - answerB-hydroxybutyrate and aceotoacetate Which of the following shuttle systems is necessary for the oxidation of long chain fatty acids? - answercarnitine B-oxidation of long chain fatty acids is inhibited by: - answerMalonyl-CoA An 11-year-old female...thirsty, frequent urination...thin, in the 30th percentile for height and weight....glucose in urine. Evaluation of bloodwork would reveal decreased levels of which of the following compounds or hormones? - answerInsulin Malate can be converted to pyruvate in the cytosol. Which of the following compounds is directly generated in this conversion and is essential for fatty acid synthesis? - answerNADPH Insulin stimulates lipogenesis through several mechanisms. Which of the following is not an insulin-stimulated process that enhances lipogenesis? - answerDecreased activity of the pyruvate dehydrogenase complex Under conditions when glucose oxidation is elevated, the acetyl CoA produced will allosterically activate which of the following enzymes leading to an increase in production of oxaloacetate? - answerpyruvate carboxylase An individual consumes a large meal consisting of a cheeseburger and fries. Which of the following intermediates is shuttled out of the TCA cycle to be used as a substrate for fatty acid synthesis? - answercitrate Fatty acid synthesis is a multimeric enzyme complex. Which of the following subunits contains pantothenic acid as a cofactor? - answerAcyl carrier protein (ACP) Under fasting conditions, acetyl CoA carboxylase will be inhibited by an increase in which of the following compounds? - answerFatty acyl-CoA The de novo synthesis of fatty acid synthase enzyme complex results in the synthesis of: - answeronly palmitic acid (C16:0) Which of the following is the regulated step of lipogenesis in eukaryotes? - answerCarboxylation of acetyl-CoA Which of the following best describes the role of HDL particles? - answerHDL particles are required for the transport of cholesterol prom peripheral tissues to the liver Which of the following lipoproteins illustrated below is most consistent with an LDL? - answer3 Analysis of a patient's serum revealed