N5334 Quiz 1 Pharmacology 2023 LATEST QUESTIONS WITH COMPLETE SOLUTIONS ALREADY VERIFIED

PCN drug-drug interactions - ANSWER -aminoglycosides -bacteriostatic antibiotics -probenecid Cephalosporin Generation 1 - ANSWER -cephalexin -cephazolin -cephadoxil Cephalosporin and PCN - ANSWER Cross allergy w/PCN Carbapenems - ANSWER not active against MRSA Vancomycin treats - ANSWER gram positive Vancomycin AE - ANSWER ototoxicity, nephrotoxicity, red man syndrome Vancomycin main danger - ANSWER Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it increases mortality Monobactams treats - ANSWER gram negative aerobic Fosfomycin treats - ANSWER enterococcus and Ecoli Aminoglycosides treat - ANSWER gram negative bacilli Aminoglycosides adverse effects - ANSWER ototoxicity and nephrotoxicity aminoglycosides peak and trough - ANSWER Peak: 30 min after IV or IM Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like zero) Sulfonamides MOA - ANSWER inhibit folic acid synthesis UTI drugs - ANSWER 1) TMP/SMZ and nitrofurantoin 2) levofloxacin & ciprofloxacin UTI in pregnancy - ANSWER TMP/SMZ, Cipro, Levo, augmentin, cephalexin recurrent UTI prophylaxis - ANSWER TMP Recurrent UTI other tx - ANSWER SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6 mos. Acute Bact Prostatitis Tx - ANSWER Floxacins Tetracycline adverse effects - ANSWER -Yellow/brown discoloration of teeth -hepatotoxicity