BYUI BIO 295 Exam 1 Questions And Answers Rated A+ New Update Assured Satisfaction

"ALZOE" - Answer-Anti Fungal Pharmacokinetic Phases - Answer-Absorption Distribution Metabolism Excretion Affects of Absorption - Answer-Lipid solubility: Hydrophobic (faster) Drug ionization: non ionized (faster) Drug formalization: smaller (faster) Affects of Distribution - Answer-Plasma Protein binding (albumin) Blood flow: liver, kidneys, brain Specific tissue barriers (BBB) - Hyrdrophobic Astrocytes - Answer-Bridge neurons and blood vessels and supply bood to neurons. Regulate what substances reach the CNS from the BBB Liver makes things more: - Answer-Hydrophilic: easier to excrete How are drugs excreted? - Answer-Renal GI Respiratory Others: saliva, sweat, breastmilk Tolerance - Answer-Metabolic: enzyme induction Pharmacodynamic: Down regulation Dependance - Answer-Psychological: AddictionPhysical: Withdrawal (life threatening) Miosis - Answer-Parasympathetic Constriction Mydriasis - Answer-Sympathetic Dialate Brimonidine (Alphagan P) - Answer-Alpha 2 Agonist Decreases release of NE in synaptic cleft Treats Glaucoma Alpha Adrenergics (Alpha 1 Agonist) - Answer-NE Effects: BP (increased), GI (decreased), pupil (dilates) dobutamine (Dobutrex) - Answer-Beta-adrenergic Receptor: B1 more than B2 Treats: Cardogenic shock dopamine (Intropin) - Answer-Beta-adrenergic Receptor: Dopaminergic, Beta 1 Treats: Septic shock High dose receptor: Alpha 1 Causes: Vasoconstriction epinephrine (Adrenalin) - Answer-Alpha-adrenergic Receptor: B1 more than B2 more than A1 (mostly B1) Treats: Cardiac arrest, acute asthma, anaphylactic shock norepinepherine (Levophed) - Answer-Alpha-adrenergic Treats: hypotension, circulatory shockrisk: extravasation (enters surrounding tissues) Alpha-adrenergis - Answer-nasal and ocular congestion tetrahydrozoline (Visine) - Answer-Alpha-adrenergic Ocular phenylephrine (Neo-synephrine) - Answer-Alpha-adrenergic Nasal phenylephrine HCl (AK-Dilate) - Answer-Causes: Mydriasis, vasoconstriction epinephrine (EpiPen) - Answer-Beta-adrenergic (non-selective) stimulates all alpha and beta receptors causes: vasodilatation, bronchoconstriction albuterol (Proventil) - Answer-Beta 2 (selective) Treats: Acute asthma, COPD