OVARIAN HYPERSTIMULATION SYNDROME Questions with complete solution 2023/2024

OVARIAN HYPERSTIMULATION SYNDROME Questions with complete solution 2023/2024 Background - correct answer OHSS is a systemic disease resulting from vasoactive products released by hyper stimulated ovaries. The pathophysiology of OHSS is characterized by increased capillary permeability, leading to leakage of fluid from the vascular compartment, with third space fluid accumulation and intravascular dehydration. Severe manifestations include a tendency to develop thrombosis, renal and liver dysfunction and acute respiratory distress syndrome (ARDS), causing serious morbidity. Although the true incidence of mortality from OHSS is unknown -Women should be informed that mild forms of OHSS are common, affecting up to 33% of in vitro fertilization (IVF) cycles and that 3-8% of IVF cycles are complicated by moderate or severe OHSS. -A diagnosis of OHSS is usually straightforward, given a history of ovarian stimulation, either by gonadotrophins or antiestrogens, followed by the typical symptoms of abdominal distension, abdominal pain, nausea and vomiting -In the UK, any death related