BCPS – Questions & Verified Answers
Anti htn of choice in pregnancy ✔️Ans - methyldopa, labetolol
AC of choice in pregnancy ✔️Ans - enox
N/v meds for pregnancy ✔️Ans - pyridoxine, doxylamine, meclizine,
dimenhydrainate
Avoid in breastfeeding ✔️Ans - opioids, contrast (x3wks after),
buproprion/varenicline
Combined hormonal contraception post partum ✔️Ans - 3 weeks if no
risk factors, 6 weeks if risk factor
Early breakthrough bleeding vs late breakthrough ✔️Ans - increase
estrogen vs increase progestin (after at least 3 month trial)
Significant reduction in birth control efficacy know from ✔️Ans -
rifampin, anticonvulsants, lamotrigine (it is decreased by OC)
Antibiotics and OC - use backup method with . . . ✔️Ans - don't have to
have an alternate unless pt uncomfort or has breakthrough bleeding
Standard estrogen component in combined oral contraceptives ✔️Ans -
20-34 mcg
Progestone only pills - missed pill if taken how late? ✔️Ans - 3 hours
Infertility at <35, >35 ✔️Ans - < 35 = 1 year of trying; > 35 = 6 mo
Treatment of HSV - initial infection ✔️Ans - acclovir 400 mg PO TID x 7-10
d (only treats symptoms; virus doesn't go away)
suppressive therapy for HSV infection - ✔️Ans - acyclovir 400 mg PO BID
or valacyclovir 500 mg po daily
,gonococcal infection treamtnet ✔️Ans - treat for chlamydia too; ceftriax
250 mg IM x 1 plus azithro
pelvic inflammatory disease ✔️Ans - cefotetan 2 g IV q12h or cefoxitin 2 g
iv q6h + doy - treat until clinical improvement
bacterial vaginosis - treatments ✔️Ans - metronidazole or clindamycin
calculation for Risk ratio ✔️Ans - RR = A/(A+B) / C/(C+D)
Calculation for odds ratio ✔️Ans - OR = A/C / B/D
analysis used for discreet data ✔️Ans - chi squared
type of analysis used for continuous data ✔️Ans - t-test, two sample if
data is split into two groups
common tests for heterogenity in meta-analyses ✔️Ans - x2 or cochrane Q
calculate number needed to treat ✔️Ans - 1/absolute risk reduction (only
calculate if stastically significant difference found)
osmolality of plasma, CNS fluid ✔️Ans - 270-300 mOsm/kg; 280-300
mOsm/kg
max osmo of peripheral injections for no pain ✔️Ans - > 900 injection
pain and buring
FD&C Act of 1938 - required proof of ? ✔️Ans - safety (thalimide)
Defauver-harris amendment of 1962 required proof of? ✔️Ans - efficacy
Generic drug pathway act was? ✔️Ans - Hatch-Waxman Act - Drug price
competition and patent term restoration acto f 1984
Durham-humphrey amendment of 1951 did what ✔️Ans - established
difference between Rx and non-rx
, SSRIs with greatest 2D6 inhibition ✔️Ans - fluoxetine, paroxetine (very
high)
SSRIs with greatest 1A2 inhibition ✔️Ans - fluvoxamine (high),
fluoxemine (med)
first line antidepressants ✔️Ans - SSRI, SNRI, mirtaz, bupro - NOT TCA bc
of suicide potential (success)
SSRI with longest half life ✔️Ans - fluoxetine
activating SSRIs ✔️Ans - sertraline, fluoxetine
sedating SSRIs ✔️Ans - paroxetine, fluvoxamine
SNRIs (names) ✔️Ans - venlafaxine, desvenlax, duloxetine,
levomilnacipran
most common side effects of SSRI, SNRIs ✔️Ans - headache, GI
complaints, sexual dysfunction
SNRI with other indications ✔️Ans - duloxetine - periph neuropathy,
fibromyalgia, muscloskeletal pain; DDI with 2D6 mes
side effects of mirtazapine ✔️Ans - sedation (at low doses), weight gain,
increased appetite, constipation, asthenia
best SSRI for pregnancy ✔️Ans - fluoxetine, sertraline, maybe bupropion
main treatments for bipolar ✔️Ans - mood stabelizers: lithium,
anticonvulsants (VPA, carbamaz - not first line); 2nd gen atypicals
lithium serum concentration goal ✔️Ans - 0.8-1, acute or 0.6-1 for
maintenance - highly renally eliminated/depend on Na concentrations
med choices for IM acute symptom managemnet of biopolar ✔️Ans - IM
aripiprazole, olanzapine, haldol/benztropine
Anti htn of choice in pregnancy ✔️Ans - methyldopa, labetolol
AC of choice in pregnancy ✔️Ans - enox
N/v meds for pregnancy ✔️Ans - pyridoxine, doxylamine, meclizine,
dimenhydrainate
Avoid in breastfeeding ✔️Ans - opioids, contrast (x3wks after),
buproprion/varenicline
Combined hormonal contraception post partum ✔️Ans - 3 weeks if no
risk factors, 6 weeks if risk factor
Early breakthrough bleeding vs late breakthrough ✔️Ans - increase
estrogen vs increase progestin (after at least 3 month trial)
Significant reduction in birth control efficacy know from ✔️Ans -
rifampin, anticonvulsants, lamotrigine (it is decreased by OC)
Antibiotics and OC - use backup method with . . . ✔️Ans - don't have to
have an alternate unless pt uncomfort or has breakthrough bleeding
Standard estrogen component in combined oral contraceptives ✔️Ans -
20-34 mcg
Progestone only pills - missed pill if taken how late? ✔️Ans - 3 hours
Infertility at <35, >35 ✔️Ans - < 35 = 1 year of trying; > 35 = 6 mo
Treatment of HSV - initial infection ✔️Ans - acclovir 400 mg PO TID x 7-10
d (only treats symptoms; virus doesn't go away)
suppressive therapy for HSV infection - ✔️Ans - acyclovir 400 mg PO BID
or valacyclovir 500 mg po daily
,gonococcal infection treamtnet ✔️Ans - treat for chlamydia too; ceftriax
250 mg IM x 1 plus azithro
pelvic inflammatory disease ✔️Ans - cefotetan 2 g IV q12h or cefoxitin 2 g
iv q6h + doy - treat until clinical improvement
bacterial vaginosis - treatments ✔️Ans - metronidazole or clindamycin
calculation for Risk ratio ✔️Ans - RR = A/(A+B) / C/(C+D)
Calculation for odds ratio ✔️Ans - OR = A/C / B/D
analysis used for discreet data ✔️Ans - chi squared
type of analysis used for continuous data ✔️Ans - t-test, two sample if
data is split into two groups
common tests for heterogenity in meta-analyses ✔️Ans - x2 or cochrane Q
calculate number needed to treat ✔️Ans - 1/absolute risk reduction (only
calculate if stastically significant difference found)
osmolality of plasma, CNS fluid ✔️Ans - 270-300 mOsm/kg; 280-300
mOsm/kg
max osmo of peripheral injections for no pain ✔️Ans - > 900 injection
pain and buring
FD&C Act of 1938 - required proof of ? ✔️Ans - safety (thalimide)
Defauver-harris amendment of 1962 required proof of? ✔️Ans - efficacy
Generic drug pathway act was? ✔️Ans - Hatch-Waxman Act - Drug price
competition and patent term restoration acto f 1984
Durham-humphrey amendment of 1951 did what ✔️Ans - established
difference between Rx and non-rx
, SSRIs with greatest 2D6 inhibition ✔️Ans - fluoxetine, paroxetine (very
high)
SSRIs with greatest 1A2 inhibition ✔️Ans - fluvoxamine (high),
fluoxemine (med)
first line antidepressants ✔️Ans - SSRI, SNRI, mirtaz, bupro - NOT TCA bc
of suicide potential (success)
SSRI with longest half life ✔️Ans - fluoxetine
activating SSRIs ✔️Ans - sertraline, fluoxetine
sedating SSRIs ✔️Ans - paroxetine, fluvoxamine
SNRIs (names) ✔️Ans - venlafaxine, desvenlax, duloxetine,
levomilnacipran
most common side effects of SSRI, SNRIs ✔️Ans - headache, GI
complaints, sexual dysfunction
SNRI with other indications ✔️Ans - duloxetine - periph neuropathy,
fibromyalgia, muscloskeletal pain; DDI with 2D6 mes
side effects of mirtazapine ✔️Ans - sedation (at low doses), weight gain,
increased appetite, constipation, asthenia
best SSRI for pregnancy ✔️Ans - fluoxetine, sertraline, maybe bupropion
main treatments for bipolar ✔️Ans - mood stabelizers: lithium,
anticonvulsants (VPA, carbamaz - not first line); 2nd gen atypicals
lithium serum concentration goal ✔️Ans - 0.8-1, acute or 0.6-1 for
maintenance - highly renally eliminated/depend on Na concentrations
med choices for IM acute symptom managemnet of biopolar ✔️Ans - IM
aripiprazole, olanzapine, haldol/benztropine
