Thermodynamics for Biochemistry - Biochemistry

THER
MODYNAMICS




E
ANABOlic A


livinggEnergy Exciting
Arrosm is an in THAT o Can
open System



· Surroundings
master mod mos




AH
atzing
A could BE : =
Ein
System Enthalpy
-

I
A Brochemical RXN MEASURES How Much
-




Energy
is



PATHWAY REgUrrED By
-


A METABOLIC A
process .




Lost Heat
SSS & -


An individual cell AHO is Favourable

↳· ·
A WHOLE THE Of OH DETERMINED
By
-

VIVE
Organism
L
Is

·
8 ↑⑳
o -
S
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of Bonds As
⑳
L

v
THE
N umber WELL As
--
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Building
. MEASURED In JONES .




Biosynthesis

AS of Disorder AH <0
chang System LosEs HEA
=
Ein
Entropy Entropy is a Measure
-




OR RANDOMNESS "THE .
UNNERSE TENdS TOWArd CHAOS" An INCREASE
. In
Entropy is =
ExOTHERMIC


THERMODYNAMICALLY FAVOURABLE WHE A dECREASE In Enropy is Not . RECALL
MOLECUTES
NORPOLAR
IN WHER
AHO
SYSTEM TAKES HEAL from
of
Surrardnungs
WHEN A
SYSTEM RELEASES HEAT , i RANSES THE Entropy THE

=
Would Be of composer Endothermic
Surroundings
A SIMILAR CASE The

Aggreghrow
.



MOLECULES WATER : WHOLE THE is a decrease
Aggregation
In


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↑ &




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.
-
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in morecues
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E
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g

:
INCREASES As MOTOw is LESS RESTRICTED




Biological Thermodynamics
folding
THERMODYNAMICS Of PROTEIN




·
·
Hydrophilic
·
Hydrophobic

proteins Hate
&

High
Evropy


[
WATER HAS LOW
Entropy
- Due To
Hydrophobic
Effects

SO S> E
WHER
PROTEINS




·mon
o· High Entropy
WATER Has




·
· ·
D
000
%
⑨
.00 .


⑧ ·o
· Proteins Have
· S Low
entropy

·
⑧




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&
o
o
·

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⑧




WATER AS7O PROTEINS ASSO