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Samenvatting Overzicht tumoren spijsvertering

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Dit document bevat een overzicht van de behandelingen van de verschillende tumoren in het spijsverteringsstelsel, gebaseerd op het boek.

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Uploaded on
January 17, 2024
File latest updated on
January 17, 2024
Number of pages
6
Written in
2023/2024
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Summary

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BEHANDELING TUMOREN SPIJSVERTERING
Algemeen: (echo)endoscopie + biopsie voor diagnose – CT voor staging (soms PET voor metastasen)

Symptomen: pijn, anorexie, vermagering, vermoeidheid, anemie + gerelateerd aan orgaan

cTNM (klinisch) <-> pTNM (pathologisch) → minstens 12 lymfeklieren onderzoeken!

SLOKDARM

Endoscopische mucosale resectie (mucosectomie): T1aN0

Totale of partiële oesofagectomie: andere tumoren zonder metastasen
+ neo-adjuvante chemo: vanaf T3 en N+

Palliatieve therapie met stenting OF radiotherapie (OF chemo): tumoren met metastasen

GASTRO-OESOFAGALE JUNCTIE (GOJ)

Type I: oesofagectomie

Type II: prox gastrectomie + chemo

Type III: totale gastrectomie

• Neo-adjuvante chemo + radio + chirurgie OF neo-adjuvante chemo + chirurgie + chemo

MAAG

CEA, CA19

GOEDAARDIGE TUMOREN (POLIEPEN , GIST)

Resectie: alle poliepen > 1,5 cm (pre-cancereus) (hyperplastisch, hamartoom (Peutz-Jeghers), adenomateus)
= polypectomie, endoscopische mucosale resectie, endoscopische chirurgische dissectie

Heelkundige wigexcisie: GIST, lipomen, fibromen, angiomen
+ neo-adjuvante immuno en adjuvante immuno: GIST

KWAADAARDIGE TUMOREN (ADENOCARCINOOM)

Curatieve maagresectie (gastrectomie) + lymfadenectomie (+ vit B12 substitutie)
= subtotaal (antrum); totaal (andere)

Neo-adjuvante chemo + maagresectie + adjuvante chemo: vanaf T3 en N+ (zonder metastasen)

Palliatieve systeemtherapie (chemo + immuno): tumoren met metastasen
(+ stenting indien stenosen)

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Eradicatie H. pylori: laaggradig lymfoom

Chemo of radio of chirurgie: hooggradig lymfoom



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