Nuclear Medicine Exam Correct 100%

In imaging with 67Ga-citrate, target-to-background ratio increases over time because of gallium concentration in tissue: remaining the same while blood clearance progresses decreasing while blood clearance progresses remaining the same while blood clearance decreases decreasing while blood clearance decreases -ANSWER remaining the same while blood clearance progresses Following the injection of 67Ga-citrate, imaging can begin: immediately at one hour at three hours at six hours -ANSWER at six hours A technologist is positioning a patient for a 67Ga-citrate imaging study and notices that a LEAP collimator is on the camera. The recommended action for the technologist to take is to: continue positioning the patient; the correct collimator is in place. change the collimator to a GAP collimator change the collimator to a medium-energy collimator change the collimator to a high-energy collimator -ANSWER change the collimator to a high-energy collimator A 67Ga image at 48 hours after injection displays bowel activity; the technologist should: be concerned that the wrong radiopharmaceutical was administered change the collimator to reduce the scatter activity from the bowel continue imaging because this is normal check to see if a radiographic study using contrast was performed -ANSWER continue imaging because this is normal When imaging abscesses it has been demonstrated that: 67Ga-citrate is superior to 111In-oxine-labeled WBC 111In-oxine-labeled WBC is superior to 111In chloride 111In chloride is superior to 111In-oxine-labeled WBC 111In chloride is superior to 67Ga-citrate -ANSWER 111In-oxine-labeled WBC is superior to 111In chloride The radionuclide used for imaging in the diagnostic assessment of prostate cancer is: 99mTc-fanolesomab 99mTc-arcitumomab 111In-capromab pendetide 111In-pentetreotide -ANSWER 111In-capromab pendetide Patient preparation for a 111In-capromab pendetide imaging procedure should include: the administration of a diuretic 24 hours prior to injection adequate hydration prior to imaging an enema the 24 hours prior to injection an enema the morning of the imaging -ANSWER an enema the morning of the imaging For optimal targeting and minimal blood pool activity, 111In-capromab pendetide imaging should begin at: 6 to 24 hours after injection 36 to 48 hours after injection 60 to 90 hours after injection 96 to 120 hours after injection -ANSWER 96 to 120 hours after injection 111In-pentetreotide acts as an analog to: glucagon neuroepinephrine calcium somatostatin -ANSWER somatostatin I-123 Iobenguane sulfate is effective in localization of which of the following? prostate and cervical cancer lymphomas pheochromocytomas and neuroblastomas neuroendocrine tumors and inflammatory disorders -ANSWER pheochromocytomas and neuroblastomas A technologist is performing a parathyroid study using 99mTc-MIBI. After the flow study. the first phase (thyroid phase) of imaging should begin: immediately 5-10 minutes 15-20 minutes 60-90 minutes -ANSWER 15-20 minutes Which if the following radiopharmaceuticals is preferred for imaging pheochromocytoma? In-111 mIBG I-123 mIBG in-111 Octreoscan In-111 pendetide -ANSWER I-123 mIBG What is the normal biodistribution for filtered sulfur colloid with sentinal lymph node imaging? injection site and lymphatic channel injection site and sentinal node injection site, lymphatic channel, and the sentinal and secondary nodes injection site, lymphatic channel, tertiary node and spleen injection site, lungs, and bone marrow -ANSWER injection site, lymphatic channel, and the sentinal and secondary nodes Indium-111 Pentetreotide is a radiolabeled analog of: insulin glucogon somatastatin diphenhydramine -ANSWER somatastatin In children, which anatomy in the chest may show physiologic uptake of Gallium-67? thyroid parathyroid thymus carina -ANSWER thymus Meta-iodobenzylguanidine (mIBG) acts as an analog of: somataostatin monocolonal antibodies norepinephrine diphenhydramine -ANSWER norepinephrine With regards to Gallium-67 biorouting, which is NOT the best valid clinical indication for Tumor imaging? Colorectal carcinoma non-hodgkin's lymphoma lung Bronchogenic carcinoma hepatocellular carcinoma -ANSWER Colorectal carcinoma All of the following procedures may be performed with 99m sulfur colloid except: gastric emptying study gastroesophageal reflux study gastrointinal bleeding localization meckel's diverticulum localization liver-spleen functional imaging -ANSWER meckel's diverticulum localization A parathyroid adenoma will concentrate which of the following radiopharmaceuticals? 123 I sodium iodide 99m Tc pertechnetate 99m Tc sestamibi both b and c all of above -ANSWER 99m Tc sestamibi The information below appears on a vial of 67Ga. Technologist prepares 3 mCi for 12:00 Noon on Nov. 3. (1-day decay factor for 67 Ga is 0.810). What is the required volume? Gallium 67 Exp Date: Nov 6 Activity in mCi: 8 Time: 12:00 Noon Volume in mL: 4 Calibration Date: Oct 30 Concentration mCi/mL: 2 Lot No.: 67-N-87 1.8 ml 2.0 ml 2.6 ml 3.5 ml 4.6 ml -ANSWER 3.5 ml Gallium-67 is an example of a radionuclide that is generator produced reactor produced cyclotron produced byproduct material -ANSWER cyclotron produced Patients who have had previously demonstrated allergic reactions to mouse proteins have an increased risk of allergic response to: Yttrium 90 ibritumomab tiuxetan I 131 tositumomab In 111 capromab pendetide all of the above A and B only -ANSWER all of the above The ability of an antibody to react with one and only one antigen is known as its: specificity sensitivity avidity affinity -ANSWER specificity Which of the following radiopharmaceuticals may be used for imaging primary breast cancer and benign parathyroid adenoma 99mTc Tetrofosmin 99mTc Timanocept 99mTc Sestamibi 99mTc Sulfur colloid -ANSWER 99mTc Sestamibi The proper administration for lymphoscintigraphy studies is intravenous intrathecal orally a subcutaneous injection -ANSWER a subcutaneous injection 99mTc sulfur colloid may be filtered for a lymphoscintigraphy study using: hemocytometer .22mm filter .22um filter a glass frit -ANSWER .22um filter Visualization of the kidneys at 48 hours is _____ on a scan using In-111 pentetreotide and ___ on a Ga67 citrate scan. Normal: abnormal normal: normal abnormal; normal abnormal; normal -ANSWER Normal: abnormal Match the radiopharmaceutical with the indications -ANSWER somatastatin recepting neuroendocrine tumors Octreoscan localization of primary or metastatic pheochromocytomas and neuroblastomas I-123 mIBG Colorectal cancer and metastasis 99mTc CEA prostate cancer metastasis In-111 Caprmab pendatide localization of sentinal node in patients with melanoma or breast cancer 99mTc Tilmanocept small cell lung cancer Ga-67 citrate Match each radionuclide with the method of localization: -ANSWER 99mTc Tilmanocept receptor binding 99mTc Sulfur Colloid for lymphoscintigraphy phagocytosis In-111 Capromab Pendetide antigen-antibody response 99mTc Sestamib