First Aid USMLE STEP 1 flashcards with complete solution

First Aid USMLE STEP 1 flashcards with complete solution follicle - answersite in lymph node of B cell localization and proliferation paracortex - answersite in lymph node that houses T cells third - answerWhat pharyngeal pouch is the thymus derived from? MHC I - answerpresent endogenously synthesized antigens? MHC II - answerpresent exogenously synthesized antigens? MHC I - answerantigen peptides are loaded onto MHC I in RER after delivery via TAP? MHC II - answerantigen loaded following release of invariant chain in an acidifed endosome? CD8 T cell - answerTcell that directly kills virus infected cells? cortex - answerWhat part of the thymus does positive selection of T cells occur in? medulla - answerWhat part of the thymus does negative selection of T cells occur in? autoimmune polyendocrine syndrome-1 - answerDeficiency of autoimmune regulator AIRE in negative selection leads to what syndrome? Th1 cell - answerHelper T cell type that secrets IFN-y? Th2 cell - answerHelper T cell type that secretes IL4, IL5, IL10, and IL13? IL 10 and TGF B - answerThe anti inflammatory cytokines? IgG - answerImmunoglobulin that can cross the placenta?