USMLE Step 1 questions Questions and Answers 100% Correct

1-α-Hydroxylase activity is increased in response to what two physiologic states? (hint: think of vitamin D activity)Hypocalcemia and hypophosphatemia A 20-year-old woman goes to the ER with ptosis, diplopia, weakness in her jaw muscles when chewing, and muscle weakness with repeated use. What is your diagnosis?Myasthenia gravis A 20-year-old woman who was recently diagnosed with a sexually transmitted disease goes to the ER with a tender, painful, swollen, and erythematous knee (monoarticular). What organism is the likely culprit?Neisseria gonorrhea (history of STD in patient with monoarticular infectious arthritis: think gonococcus) A 25-year-old black woman presents with nonproductive cough, shortness of breath, fatigue, and malaise; she has bilateral hilar lymphadenopathy on chest radiography and elevated ACE levels. What do you diagnose?Sarcoidosis A 70-year-old man complains of urinary urgency, nocturia, hesitancy, postvoid dribbling, urinary retention, and a PSA result of 6.5 ng/mL. What is your diagnosis?BPH. Although an argument can be made for prostatic cancer (you should expect a much higher PSA result), these are buzzwords for BPH. Prostatic cancer is usually silent until late in the disease, when obstructive symptoms begin to occur. A complete opposite expression of your inward feeling (e.g., arguing all the time with someone you are attracted to when your feelings are not known)Reaction formation A Japanese man has weight loss, anorexia, early satiety, epigastric abdominal pain, and a palpable left supraclavicular lymph node. On endoscopy you find a large, irregular ulcer with elevated margins on the lesser curvature of the stomach. What is your diagnosis?Gastric carcinoma A motor lesion to the right CN V results in deviation of the jaw to which side?A right CN V lesion results in weakened muscles of mastication, and the jaw deviates to the right. A patient goes to the ER with abdominal cramps, vomiting, diarrhea, and sweating less than 24 hours after eating potato salad at a picnic; what is the most likely responsible organism?Staphylococcus aureus A single mRNA strand translated by a ribosome is termed what?Polysome. Ribosomes read from the 5' to the 3' end of the mRNA. A suspected dermatophyte infection is stained with KOH. What spore type do you expect to see?Arthroconidia with hyphae A tropical fish enthusiast has granulomatous lesions and cellulitis; what is th