ABGC Practice Exam | Questions with 100% Correct Answers | Verified | Latest Update 2024

Under what circumstances should an infant with clinical features of Down syndrome be karyotyped? A. Only if the parents desire more children B. Only if the mother is younger than 35 years old C. Only if not all of the features of Down syndrome are present D. Only if the mother has had 3 early miscarriages E. Always - E. Always What is the parental origin and stage of meiosis when most meiotic errors occur resulting in chromosomal trisomy? A. Maternal meiosis I B. Paternal meiosis I C. Maternal meiosis II D. Paternal meiosis II E. Maternal meiosis I and II are equally likely - A. Maternal meiosis I A 23-year-old woman has a baby with the karyotype 47,XY,+21. Which of the following is the correct conclusion? A. This woman's risk for having another baby with a chromosome abnormality is the same as other women her age B. Either the woman or her husband probably has a Robertsonian translocation C. Either the woman or her husband probably has germ line mosaicism D. Either the woman or her husband probably carriers a balanced reciprocal translocation E. Both members of the couple probably have normal chromosomes - E. Both members of the couple probably have normal chromosomes