PC707 Module 2 Questions and Answers (Graded A+)

Which antibiotic is the drug of choice for MRSA - ANSWER-Beta-lactam antibiotic What is the first step in treating a MRSA Abscess? - ANSWER-I&D with culture followed by CDC gold standard resource for plan of care and abx selection if necessary What is the risk of using tetracycline and calcium/dairy products? - ANSWER-Chelate formation from the calsium What abx is associated with serious adverse effects of hyperkalemia? - ANSWER-Trimethoprim-sulfamethazole Trimethoprim-sulfamethazole plus this med increases risk of hyperkalemia and sudden cardiac death? - ANSWER-ACE Inhibitor or angiotensin receptor blocker Most serious Warfarin/drug interaction - ANSWER-Trimethoprim-Sulfamethazole will increase INR and risk bleeding These drugs increase INR in pts taking warfarin - ANSWER-TMP-SMX, erythromycin, fluconazole, ketoconazole, itraconazole, metronizadole Simvastatin or Lovestatin are HMG-CoA ihibitors metabolyzed by CYP3A4 system and should not be taking with what drug? - ANSWER-Biaxin (clarithromycin) Clarithrymycin interacts with these drugs to cause severe kidney injury - ANSWER-Calcium Channel blockers Fluoroquinolone/levofoxacin (Levaquin) can cause tendon rupture in what patients? - ANSWER-Over 60, with corticosteroids, organ transplant patients. Risk factors for development of antibiotic resistant Otitis Media - ANSWER-Day care, less than 2 years old, abx in last 3 mths, winter/spring, local resistance pattern via antibiogram Gram Positive Pathogens - ANSWER-1. Staph, 2. Strep, 3. Enterococci Why does C.Diff result? - ANSWER-C. Diff colonizing the normal gut flora resulting in toxin release Four abx that cause C.Diff - ANSWER-1. Imipenem, 2. Ceftazidime, 3. clindamycin, 4. moxifloxacin Tx of choice for mild/mod c. Dif - ANSWER-Metronidazole 500mg PO TID x 10-14 days Tx of choice for severe C. Diff - ANSWER-oral Vanco