Galen 265 Exam 4 Part 1

Discoid Lupus - Affects skin, isn't lethal Discoid lupus presents with ... - Macular Rash or Discoid Rash Discoid rash - red raised patches with scaling skin Malar Rash - Red flat or raised over cheeks (butterfly rash) Discoid Lupus Diagnostics - Skin Biopsy SLE - Chronic, progressive, Inflammation of connective tissue, and affects multiple body systems SLE in kidneys - Leading cause of death, presents with high creatinine, low hematocrit, proteinuria SLE is most common in ... - women 20yr- 40yr SLE manifestations - Rash, Photosensitivity, oral ulcers, polyarthritis, pericarditis, plural effusion, FEVER, fatigue, weakness, anorexia,weight loss, proteinuria, seizures,peripheral neuropathy, psychosis, Raynauds, alopecia SLE diagnostics - ANA test, C Reactive Protein test( is normal w/ SLE flare up), CBC( shows pancytopenia) SLE meds - Topical steroids, NSAIDs (caution with kidneys), Hydroxychloroquine, Glucocorticiods, Immunosuppressants: Methotrexate, Azathioprine, Belimumab Glucocorticiods - Give before breakfast, take C+ supp, monitor skin integrity. Hydroxychloroquine - Frequent eye exams. eye exam before starting med and q 6 months Belimumab - DO NOT receive live vaccines for 30 days before tx SLE teaching - MONITOR TEMP!!( first sign of worsening), limit sun exposure, wide brim hat, long sleeves, sunscreen SPF 30+ , clean w/ mild soap, pat dry,mosturize, avoid alot of powder cosmetics, avoid large crowds, pregnancy can cause exacerbation. No harsh hair tx. scleroderma - uncommon, chronic, autoimmune inflammatory disease. Scleroderma causes... - fibrosis in tissue and then hardening of tissue. Diffuse cutaneous scleroderma - = major organ problems Limited cutaneous scleroderma - = esophagus problems Diffuse cutaneous scleroderma manifestations - 1st sx= edema in hands an w/ or w/o bilateral carpel tunnel thickened skin on trunk, face, proximal and distal extremities. GERD, Dysphagia, Myocardial fibrosis, malignant hypertension, lung fibrosis and PAH. Complications are rapid