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Summary Cell Junctions Overview

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Basic overview of types of cell junctions and what their role is, including diagrams of junctions.

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December 5, 2023
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2023/2024
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Cell Junctions Overview

Types:
● Tight junctions
● Adherens junctions
● Desmosomes
● Hemi-desmosomes
● Gap junctions




Tight Junctions
● Regulate transport of molecules between
epithelial cells
● Preserve epithelial polarity - serves as a ‘fence’,
preventing diffusion of plasma membrane
proteins between basal and apical regions




Adherens Junctions
● Family of related cell surface domains
● Link neighbouring cells together




Desmosomes
● Provide structural stability to
sheets of epithelial cells
● Link intermediate filament
networks of neighbouring cells
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