Cell Junctions Overview
Types:
● Tight junctions
● Adherens junctions
● Desmosomes
● Hemi-desmosomes
● Gap junctions
Tight Junctions
● Regulate transport of molecules between
epithelial cells
● Preserve epithelial polarity - serves as a ‘fence’,
preventing diffusion of plasma membrane
proteins between basal and apical regions
Adherens Junctions
● Family of related cell surface domains
● Link neighbouring cells together
Desmosomes
● Provide structural stability to
sheets of epithelial cells
● Link intermediate filament
networks of neighbouring cells
Types:
● Tight junctions
● Adherens junctions
● Desmosomes
● Hemi-desmosomes
● Gap junctions
Tight Junctions
● Regulate transport of molecules between
epithelial cells
● Preserve epithelial polarity - serves as a ‘fence’,
preventing diffusion of plasma membrane
proteins between basal and apical regions
Adherens Junctions
● Family of related cell surface domains
● Link neighbouring cells together
Desmosomes
● Provide structural stability to
sheets of epithelial cells
● Link intermediate filament
networks of neighbouring cells