NSG 6005 Advanced Pharmacology Final Exam
Review – Qs And As
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy? ✔️Ans - To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? ✔️Ans -
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a
low TSH level with? ✔️Ans - Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)?
✔️Ans - Aldosterone antagonist
Heparin exerts its therapeutic action by what? ✔️Ans - Upregulating
the activity of one of the body's natural anticoagulant molecules,
antithrombin III
What physiologic action happens when the offending drug is administered
during an anaphylactic reaction. ✔️Ans - Mast cells liberate large doses
of histamine.
What are two systemic psoriasis medications? ✔️Ans - Photo-therapy
and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension? ✔️Ans - Thiazide diuretics
What is the effect of cardiac glycosides? ✔️Ans - Digitalis glycosides
have a negative chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control
medication? ✔️Ans - Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for
available beta-receptor sites? ✔️Ans - Atenolol (Tenormin)
, What type of action does nitrates have on the body? ✔️Ans - Reduction
in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol
(LDL) for patients with known coronary artery disease? ✔️Ans -
100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? ✔️Ans -
Depressing phase 4 depolarization and lengthening phases 1 and 2
repolarization.
Which drug therapy should be used to lower the serum concentration of
thyroid hormones and re-establish eumetabolic state in a patient with
Graves' disease? ✔️Ans - Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient
with renal insufficiency? ✔️Ans - Loop diuretic.
What drug should be considered as first-line therapy for a client with
hypertension and heart failure? ✔️Ans - Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during
pregnancy? ✔️Ans - Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker?
✔️Ans - Prazosin (Minipress)
What is an expected effect of the use of a beta-adrenergic blocker to control
angina? ✔️Ans - Reduced force of cardiac contraction.
What side effect should be monitored closely in the elderly when taking
Metformin (Glucophage) for type 2 diabetes? ✔️Ans - Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? ✔️Ans -
Deactivate and detoxify medications and other substances.
What is a component of Vitamin K-dependent clotting factors? ✔️Ans -
Prothrombin
Review – Qs And As
Why are nitrate-free periods every 24 hours necessary for the patient on
nitroglycerin therapy? ✔️Ans - To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? ✔️Ans -
Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a
low TSH level with? ✔️Ans - Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)?
✔️Ans - Aldosterone antagonist
Heparin exerts its therapeutic action by what? ✔️Ans - Upregulating
the activity of one of the body's natural anticoagulant molecules,
antithrombin III
What physiologic action happens when the offending drug is administered
during an anaphylactic reaction. ✔️Ans - Mast cells liberate large doses
of histamine.
What are two systemic psoriasis medications? ✔️Ans - Photo-therapy
and topical corticosteroids
What is the first choice of drug therapy for the majority of patients with
uncomplicated stage I hypertension? ✔️Ans - Thiazide diuretics
What is the effect of cardiac glycosides? ✔️Ans - Digitalis glycosides
have a negative chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control
medication? ✔️Ans - Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for
available beta-receptor sites? ✔️Ans - Atenolol (Tenormin)
, What type of action does nitrates have on the body? ✔️Ans - Reduction
in systemic venous tone.
What is the recommended level of low-density lipoprotein cholesterol
(LDL) for patients with known coronary artery disease? ✔️Ans -
100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? ✔️Ans -
Depressing phase 4 depolarization and lengthening phases 1 and 2
repolarization.
Which drug therapy should be used to lower the serum concentration of
thyroid hormones and re-establish eumetabolic state in a patient with
Graves' disease? ✔️Ans - Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient
with renal insufficiency? ✔️Ans - Loop diuretic.
What drug should be considered as first-line therapy for a client with
hypertension and heart failure? ✔️Ans - Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during
pregnancy? ✔️Ans - Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker?
✔️Ans - Prazosin (Minipress)
What is an expected effect of the use of a beta-adrenergic blocker to control
angina? ✔️Ans - Reduced force of cardiac contraction.
What side effect should be monitored closely in the elderly when taking
Metformin (Glucophage) for type 2 diabetes? ✔️Ans - Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? ✔️Ans -
Deactivate and detoxify medications and other substances.
What is a component of Vitamin K-dependent clotting factors? ✔️Ans -
Prothrombin
