Multiple Sclerosis – Patho questions with correct answers

1. What arm of the nervous system is involved in MS (i.e., central or pheripheral)?What specifically does the immune system "attack" in multiple sclerosis? Give examples of what affect this will have nervous system. CORRECT ANSWER-• Central, which consist of the brain and spinal cord; • Myelin sheath; o Visual disturbances o Loss of sensation o Loss of coordination and balance o Bladder and bowel dysfunction o Attention deficit, memory loss o Muscle fatigue and numbness 2. Why was this disease called "multiple sclerosis"? CORRECT ANSWER-Multiple = many, sclerosis = scars; in pt. with MS, MRI shows many plaques consisting of inflammatory cells, edema and destroyed myelin fragments 3. What are the four functions of astrocytes? CORRECT ANSWER-• Formation of the Blood-brain barrier: the astrocyte end-feet encircling endothelial cells of the capillaries form part of the blood-brain barrier; • Neurotransmitter reuptake and release; • Regulation of ion concentration in the extracellular space; • Promotion of the myelinating activity of oligodendrocytes. 4. What is the function of microglia cells? Oligondendrocytes? CORRECT ANSWER-• Microglia cells are t