Please check the examination details below before entering your
candidate information
Candidate surnameOther names
Centre Number Candidate Number
Pearson Edexcel Level 3 GCE
Friday 16 June 2023
9BN0/00
Paper
Morning (Time: 2 hours)
reference
Biology A (Salters Nuffield) 002222
Advanced
PAPER 2: Energy, Exercise and Coordination
You must have: Total Marks
Scientific calculator, pencil, ruler
Instructions
•name, centre number and candidate number.
• Use black ink or ball-
Fill in the boxes at the top of this page with your
point pen.
• Answer
•Show
all
your working in any calculation questions and include units in
your answer where appropriate.
•questions.
Answer the questions in the spaces
provided – there may be more space
than you need.
Information
•– use this as a guide as to how much time to spend on
• The total mark for this paper
The marks for each question are shown in brackets
•iseach
100.
question. You may use a scientific calculator.
•your ability tomarked
In questions with an asterisk (*), marks will be awarded for
structure your answer logically showing how the points
that you make are related or follow on from each other where
appropriate.
Advi
•
ceRead each question carefully before you start to answer it.
• Try to answer every
• Check your answers if you have time at Turn over
question.
the end.
, Answer ALL questions.
Write your answers in the spaces provided.
AREA
DO NOT WRITE IN THIS
Some questions must be answered with a cross in a box . If
you change your mind about an answer, put a line through the box
and then mark your new answer with a
cross .
1 During growth, cells divide by mitosis. Many organisms also carry
out meiosis to enable sexual reproduction.
(a) (i) In which stage of cell division do spindle fibres attach to the centromeres?
(1)
A anaphase
B interphase
C metaphase
D telophase
(ii) In which stage of the cell division does the nuclear
AREA
DO NOT WRITE IN THIS
membrane start to break down?
(1)
A interphase
B metaphase
C prophase
D telophase
(iii) In which stage of cell division are chromatids first visible
when using a light microscope?
(1)
A interphase
B metaphase
C prophase
AREA
DO NOT WRITE IN THIS
D telophase
, (b) Meiosis is involved in the production of sperm
cells. Crossing over during meiosis can result in
DO NOT WRITE IN THIS
genetic variation. Explain how crossing over can
lead to genetic variation.
(3)
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(Total for Question 1 = 6 marks)
AREA
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AREA
, 2 It has been estimated that up to 90% of the cells present in a human
are prokaryotic.
AREA
DO NOT WRITE IN THIS
This is due to prokaryotes being present on the skin surface
and within the human body.
(a) Which one of the following statements comparing prokaryotic
DNA with human DNA is correct? (1)
A prokaryotic DNA is linear and human DNA is circular
B prokaryotic DNA is located in a membrane-bound nucleus
C the base thymine is replaced by uracil in the prokaryotic
DNA
D the sugar in both eukaryotic and prokaryotic DNA is
deoxyribose
(b) The lac operon is found in some prokaryotes. (2)
(i) Describe what is meant by the term operon.
AREA
DO NOT WRITE IN THIS
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(ii) Describe the effect of lactose on the lac operon.
(3)
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AREA
DO NOT WRITE IN THIS
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(Total for Question 2 = 6 marks)
candidate information
Candidate surnameOther names
Centre Number Candidate Number
Pearson Edexcel Level 3 GCE
Friday 16 June 2023
9BN0/00
Paper
Morning (Time: 2 hours)
reference
Biology A (Salters Nuffield) 002222
Advanced
PAPER 2: Energy, Exercise and Coordination
You must have: Total Marks
Scientific calculator, pencil, ruler
Instructions
•name, centre number and candidate number.
• Use black ink or ball-
Fill in the boxes at the top of this page with your
point pen.
• Answer
•Show
all
your working in any calculation questions and include units in
your answer where appropriate.
•questions.
Answer the questions in the spaces
provided – there may be more space
than you need.
Information
•– use this as a guide as to how much time to spend on
• The total mark for this paper
The marks for each question are shown in brackets
•iseach
100.
question. You may use a scientific calculator.
•your ability tomarked
In questions with an asterisk (*), marks will be awarded for
structure your answer logically showing how the points
that you make are related or follow on from each other where
appropriate.
Advi
•
ceRead each question carefully before you start to answer it.
• Try to answer every
• Check your answers if you have time at Turn over
question.
the end.
, Answer ALL questions.
Write your answers in the spaces provided.
AREA
DO NOT WRITE IN THIS
Some questions must be answered with a cross in a box . If
you change your mind about an answer, put a line through the box
and then mark your new answer with a
cross .
1 During growth, cells divide by mitosis. Many organisms also carry
out meiosis to enable sexual reproduction.
(a) (i) In which stage of cell division do spindle fibres attach to the centromeres?
(1)
A anaphase
B interphase
C metaphase
D telophase
(ii) In which stage of the cell division does the nuclear
AREA
DO NOT WRITE IN THIS
membrane start to break down?
(1)
A interphase
B metaphase
C prophase
D telophase
(iii) In which stage of cell division are chromatids first visible
when using a light microscope?
(1)
A interphase
B metaphase
C prophase
AREA
DO NOT WRITE IN THIS
D telophase
, (b) Meiosis is involved in the production of sperm
cells. Crossing over during meiosis can result in
DO NOT WRITE IN THIS
genetic variation. Explain how crossing over can
lead to genetic variation.
(3)
............................................................................................................................... ...............................................................................................
................................ ......................
AREA
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
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................................ ......................
DO NOT WRITE IN THIS
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
................................ ......................
(Total for Question 1 = 6 marks)
AREA
DO NOT WRITE IN THIS
AREA
, 2 It has been estimated that up to 90% of the cells present in a human
are prokaryotic.
AREA
DO NOT WRITE IN THIS
This is due to prokaryotes being present on the skin surface
and within the human body.
(a) Which one of the following statements comparing prokaryotic
DNA with human DNA is correct? (1)
A prokaryotic DNA is linear and human DNA is circular
B prokaryotic DNA is located in a membrane-bound nucleus
C the base thymine is replaced by uracil in the prokaryotic
DNA
D the sugar in both eukaryotic and prokaryotic DNA is
deoxyribose
(b) The lac operon is found in some prokaryotes. (2)
(i) Describe what is meant by the term operon.
AREA
DO NOT WRITE IN THIS
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
................................ ......................
(ii) Describe the effect of lactose on the lac operon.
(3)
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
................................ ......................
............................................................................................................................... ...............................................................................................
................................ ......................
AREA
DO NOT WRITE IN THIS
............................................................................................................................... ...............................................................................................
................................ ......................
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(Total for Question 2 = 6 marks)
