CCRN- Hematology Concepts (Barron's) questions with correct answers

platelet -platelet plug (white clot) is effective for small injuries -ordinarily, platelets do not react with endothelium; BUT in the presence of injury, platelets become activated and actually change shape and appearance CORRECT ANSWER-the smallest of blood cells, made in bone marrow; 200 billion produced per day, greater than 1 trillion circulating at all times; white, live 7-10 days activated platelets--> secrete ADP--> activation of COX pathway--> phospholipase 2 mediated--> thromboxane A2 produced--> further activation of platelets to area--> platelet plug forms in 1-4 minutes after injury CORRECT ANSWER-what is the physiology of platelet "white" clot formation? (figure 11-1 pg 212) platelet count; bleeding time CORRECT ANSWER-(platelet count, bleeding time) measures platelet quantity while (platelet count, bleeding time) measure platelet function, how well platelets work intrinsic coagulation pathway CORRECT ANSWER-this pathways is stimulated by vascular endothelium injury 1) cell trauma (valve, IABP) 2) sepsis 3) shock 4) ARDS 5) hypoxemia, acidemia 6) cardiopulmonary arrest CORRECT ANSWER-what are 6 things that stimulate the intrinsic coagulation path