MLT ASCP Chemistry Practice Questions And Answers 100% Correct!!

MLT ASCP Chemistry Practice Questions And Answers 1 Which one of the following statements about acetaminophen metabolism is false? Choose the single best answer A. It is metabolized in the kidney B. It is largely metabolized in the liver to glucuronide and sulfonate conjugates C. A small amount is metabolized via cytochrome oxidase to a reactive benzoquinoneimine intermediate D. This intermediate becomes toxic to the liver once tissue glutathione becomes depleted - ANSWER-A; The benzoquinoneimine intermediate produced in the liver as a result of hepatic cytochrome oxidase metabolism of acetaminophen is responsible for hepatic necrosis via acylation of hepatic tissue. The treatment of acetaminophen toxicity includes the use of N-acetylcysteine (Mucomyst), which acts as a glutathione substitute. The risk of hepatotoxicity is predicted with the Rumack-Matthew nomogram, which uses the hours after ingestion and plasma acetaminophen level to predict the probability of hepatotoxicity. Severe hepatotoxicity can be fatal. According to the 2010 ADA guidelines, HbA1C percent can be used as an assay to diagnose diabetes. True/False - ANSWER-T; The 2010 ADA Clinical Practice Recommendations added measurement of HbA1C as a diagnostic assay for diagnosis of diabetes. Which of the following conditions would make a sample unsuitable for lactic acid testing? Choose the single best answer A. Movement of hand or arm during specimen collection B. Received in the lab on ice C. Centrifuged in a refrigerated centrifuge D. Specimen centrifuged and plasma separated from cells less than 15 minutes after collection - ANSWER-A; Movement of the muscles in the hand or arm during specimen collection will falsely increase lactic acid concentration. A blood sample for lactic acid testing should be 00% Correct!!