NR565 FINAL EXAM STUDY MATERIAL 2023/2024

Criteria for dx DM - CORRECT ANSWER-Fasting plasma glucose greater than 126 Random plasma glucose greater than 200 Oral glucose tolerance test greater than 200 HgA1c at or greater than 6.5% What drug class should be considered for DM before insulin - CORRECT ANSWERBiguanide (Metformin) Action of Insulin - CORRECT ANSWER-Synthesized in pancreas, primary metabolic action is anabolic. Promotes conservation of energy and buildup of energy stores like glycogen. MOA Sulfonylureas - CORRECT ANSWER-by stimulating release of insulin from pancreatic islets. If pancreas is not capable of insulin synthesis, they will not be effective. thus, cannot use on DM1 only DM2 Glinides MOA - CORRECT ANSWER-by stimulating release of insulin from pancreatic islets. If pancreas is not capable of insulin synthesis, they will not be effective. thus, cannot use on DM1 only DM2 Thiazolidinediones (TZD) MOA - CORRECT ANSWER-Decrease glucose levels