Nurs 2514 CAD Pharmacology 100% SOLUTIONS GUARANTEE

Nurs 2514 CAD Pharmacology 100% SOLUTIONS GUARANTEE What are the two Lipid lowering agents? - ANSWER •HMG-CoA Reductase Inhibitors (Atorvastatin) •Bile-Acid Sequestrants (Colesevelam) _______ is a CCB (Ca Channel Blocker) - ANSWER Verapamil What are the different nitrates? - ANSWER Sublingual Nitroglycerin Isosorbide Dinitrate Morphine (learned in 2500) Clopidogrel is a __________________ - ANSWER Adenosine Diphosphate Receptor Antagonist What drug class is HMG -CoA reducatase inhibitor? - ANSWER Lipid lowering drug therapy -- often ends with "statin" •Lowers LDL (25%-60%) and total cholesterol •increases HDL (5-22%) True or False: Atorvastatin -Lipitor helps to lower the risk of heart failure, MI and sudden death - ANSWER True, there is a significant reduction of LDL in 2 weeks but effects might stop if the drug is stopped What is the MOA of Atorvastatin? - ANSWER - competitively inhibits of HMG CoA reductase so less HMG CoA = lowers the amount of cholesterol production - decreased cholesterol conc stimulates upregulation of LDL receptors + increase HDL to recruit LDL = increased uptake of LDL What is the indication of Atorvastatin? - ANSWER •hypercholesterolemia, (elevated LDL cholesterol levels) •1°and 2° prevention of cardiovascular (CV) events (even those with normal LDL) •diabetes What is the adverse effects of atorvastatin? - ANSWER •generally well tolerated Common: •headache, r