ASCP (SBB) BOC PREPARATION EXAM (LATEST UPDATE)
QUESTIONS AND ANSWERS (GRADED A)
Chemicals that send signals between cells are
Cytokines
Antibodies are made by what cells?
Plasma cells
Where do B cells mature?
Bone Marrow
Where do T cells mature?
Thymus
Coating of a cell with antibodies or complement is called?
Opsonization
CD4 + cells are?
T helper cells
The specific chemical group that provokes an antibody response
Epitope
,Blood groups are made of two main kinds of chemicals
Proteins, carbohydrates
What is the function of the FC piece of an immunoglobulin?
Monocyte binding
What is the only Ig that crosses the placenta?
IgG
What does 2-ME OR DTT do to IgM antibodies?
Destroys disulfide bonds
Which is the secretory Ig?
IgA
Which Ig is responsible for allergic reaction's?
IgE
Which IgG subclass does not bind complement?
IgG4
, Which IgG sub classes are most clinically significant?
IgG 1 & 3
What is isotype switching?
Example IgM switches to IgG
What is the end point of complement activation?
Hole in cell
At what stage of complement cascade is it amplified?
C3 activation
What two ions are needed for complement activity?
Ca++ and Mg++
Name two complement components that are anaphylatoxins
C3a and C5a
What is the minimum number of days a BBK specimen must be kept?
Seven days post transfusion
QUESTIONS AND ANSWERS (GRADED A)
Chemicals that send signals between cells are
Cytokines
Antibodies are made by what cells?
Plasma cells
Where do B cells mature?
Bone Marrow
Where do T cells mature?
Thymus
Coating of a cell with antibodies or complement is called?
Opsonization
CD4 + cells are?
T helper cells
The specific chemical group that provokes an antibody response
Epitope
,Blood groups are made of two main kinds of chemicals
Proteins, carbohydrates
What is the function of the FC piece of an immunoglobulin?
Monocyte binding
What is the only Ig that crosses the placenta?
IgG
What does 2-ME OR DTT do to IgM antibodies?
Destroys disulfide bonds
Which is the secretory Ig?
IgA
Which Ig is responsible for allergic reaction's?
IgE
Which IgG subclass does not bind complement?
IgG4
, Which IgG sub classes are most clinically significant?
IgG 1 & 3
What is isotype switching?
Example IgM switches to IgG
What is the end point of complement activation?
Hole in cell
At what stage of complement cascade is it amplified?
C3 activation
What two ions are needed for complement activity?
Ca++ and Mg++
Name two complement components that are anaphylatoxins
C3a and C5a
What is the minimum number of days a BBK specimen must be kept?
Seven days post transfusion
