NR 546 Week 8 Neurotransmitter Table Chamberlain

NR 546 Week 8 Neurotransmitter Table Chamberlain. Neuro transmitter Receptor Subtype Location/Function/Effects /symptoms of excess or deficit if applicable Distribution (ie: CNS/PNS, GI, vascular) Drug classes that target this neurotransmitter or receptor Specific medications that target this neurotransmitter or receptor Glutamate AMPA α-Amino-3-hydroxy-5- methyl-4- isoxazolepropionic acid (AMPA)-type glutamate receptors (AMPARs) mediate the majority of fast excitatory synaptic transmission in the brain. AMPA receptors are abundant and widely distributed in the central nervous system. Hippocampus, outer layer of the cortex, basal ganglia, olfactory regions, lateral septum, and amygdala of the CNS are all enriched with GluA1, GluA2, and GluA3 subunits. CNS AMPA Receptor Antagonists Perampanel MNDA N-methyl-D-aspartate (NMDA) receptors represent one of the ligand-gated non-selective ionotropic glutamate receptors (iGluRs), which CNS NMDA receptors are found in both synaptic and extrasynaptic NDMA Glutamate Antagonist NDMA Glutamate AntagonistMemantine Phencyclidine Ketamine Dextromethorphan Dextromethadone