Test 3 review Wilkes N552 questions and answers.

Dementia • Treating comorbidites such as depression-consider the whole picture Dementia Pharmacologic-Review side effects and rationales for use Rivastigmine Memantine Donepezil Galantamine Know what is indicated for dementia and the side effects. Know the difference between delirium and dementia and how to rule one out and the other in. Delirium • Differentiate from dementia Identify etiology and TREAT underlying cause Autism and IDD • No pharmacological treatments for IDD itself, but behavioral therapy can be implemented and if necessary, pharmacological options for behavioral control. Must be vigilant about monitoring for SE due to I potential communication problems Limited for Autism- only for agitation/behavioral dyscontrol related to autism. Frequently antipsychotics used. Be wary of side effects, metabolic syndrome, sedation, etc ADHD stimulants Review side effects, indications, significant drug-drug interactions, half-life and formulation (long acting vs immediate release) and I relative pros/cons. What baseline studies should be completed prio to initiation, first line therapy ADHD initiation, first Non-stimulants • Atomoxetine, guanfacine, clonidine ADHD Again, knowing the onset and half-life of the available medications, especially the stimulants will be helpful. Know the difference between guanfacine and clonidine and when to use. Know monitoring requirements for ADHD treatment. Know what treatments are first line. • Acute Intoxication- Opioids Tx with naloxone. Respiratory depression Hypotension Bradycardia Hypothermic Miosis Opioids • Withdrawal Increased lacrimation • Muscle aches Abdominal cramps and diarrhea Opioid use and treatment • Naloxone-MOA µ-opioid antagonist Naltrexone-MOA Buprenorphine- MOA- mu opioid receptor partial agonist. Buprenorphine/Naloxone- Suboxone • Acute intoxication - Tx IV benzodiazepines Agitation Violent Muscle twitches Hypertension Tachycardia Hyperthermic Hallucinations Mydriasis • Acute intoxication- Tx Alcohol supportive only Confusion Slurred speech Poor balance slowed responses and reaction time Vomiting Impaired judgment Withdrawal Alcohol can be life threatening- Tx with benzodiazepines Tremors Seizures Elevated LFT Delirium Tremers Alcohol abstinence. Meds Naltrexone Disulfiram Acamprosate Nicotine • Assessment • 5 A's • Treatment Nicotine replacement therapy Bupropion Verenicline Behavioral modification