Advanced Pharmacology NR 565 Final Exam Questions and Verified Answers

What labs are used to diagnose thyroid problems? Free and total T3 Free and total T4 TSH Anti-TPO Hypothyroidism labs - increased TSH, decreased T3 &T4 hyperthyroidism labs - decreased TSH and increased T3 &T4 When to recheck labs after starting levothyroxine? - 6-8 weeks or after dose change, then 12 months once stabilized S/S hypothyroidism - pale, puffy, and expressionless face, cold and dry skin, brittle hair/hair loss, low heart rate and body temperature, lethargy, fatigue, cold intolerance, mental status changes, thyroid enlargement Think "hypo low and slow" S/S hyperthyroidism - strong and rapid heart rate, dysrhythmias, angina, nervousness, insomnia, rapid thought flow and speech, muscle weakness/atrophy, increased metabolic rate (increased heat production, increased body temperature, heat intolerance), warm/moist skin, increased appetite, weight loss despite increased caloric intake think "hyper as in fast" result of not treating hypothyroidism during pregnancy - permanent neuropsychological deficits in the child. First trimester: fetus unable to produce their own thyroid hormones. Fetal thyroid gland is fully functional in the second trimester. Medication to treat SYMPTOMS of hyperthyroidism - beta blocker (decrease HR) non-radioactive iodineHow to take levothyroxine with food? - take on an empty stomach in the morning, 30-60 minutes before breakfast Supplement/drug interactions with levothyroxine - antacids, iron, calcium