Question 1 1 / 1 point
Severe contact dermatitis caused by poison ivy or poison oak exposure often requires treatment with:
Oral corticosteroids for 2 to 3 weeks
Thickly applied topical intermediate-dose corticosteroids
Isolation of the patient to prevent spread of the dermatitis
Question 2 1 / 1 point
Patrick is a 10-year-old patient who presents with uncomfortable constipation. Along with diet changes, a laxative is ordered to provide more rapid relief of constipation. An appropriate choice of medication for a 10-year-old child would be:
PEG 3350 (Miralax)
Bisacodyl (Dulcolax) suppository
Docusate (Colace) suppository
Polyethylene glycol electrolyte solution
Question 3 1 / 1 point
Patients who are on chronic long-term proton pump inhibitor therapy require monitoring for:
Iron deficiency anemia, vitamin B12 and calcium deficiency
Folate and magnesium deficiency
Elevated uric acid levels leading to gout
Hypokalemia and hypocalcemia
Question 4 1 / 1 point
The drug of choice for treatment of early latent or tertiary syphilis is:
Benzathine penicillin G IM
Question 5 0 / 1 point
The optimal maximum time frame for HRT or estrogen replacement therapy (ERT) is:
Question 6 1 / 1 point
The Best Pharmaceuticals for Children Act:
Includes a pediatric exclusivity rule which extends the patent on drugs studied in children
Establishes a committee that writes guidelines for pediatric prescribing
Provides funding for new drug development aimed at children
Encourages manufacturers specifically to develop pediatric formulations
Question 7 1 / 1 point
Sophie presents to the clinic with a malodorous vaginal discharge and is confirmed to have Trichomonas infection. Treatment for her would include:
Metronidazole 2 grams PO x 1 dose
Topical intravaginal metronidazole daily x 7 days
Intravaginal clindamycin daily x 7 days
Azithromycin 2 grams PO x 1 dose
Question 8 1 / 1 point
Jamison has been prescribed citalopram (Celexa) to treat his depression. Education regarding how quickly selective serotonin reuptake inhibitor (SSRI) antidepressants work would be:
Appetite and concentration improve in the first 1 to 2 weeks.
Sleep should improve almost immediately upon starting citalopram.
Full response to the SSRI may take 2 to 4 months after he reaches the full therapeutic dose.
His dysphoric mood will improve in 1 to 2 weeks.
Question 9 1 / 1 point
Patients who have a poor metabolism phenotype will have:
Slowed metabolism of a prodrug into an active drug, leading to accumulation of Prodrug
Accumulation of inactive metabolites of drugs
A need for increased dosages of medications
Increased elimination of an active drug
Question 10 1 / 1 point
The drug of choice for type 2 diabetics is metformin. Metformin:
Decreases glycogenolysis by the liver
Increases the release of insulin from beta cells
Increases intestinal uptake of glucose
Prevents weight gain associated with hyperglycemia
Question 11 1 / 1 point
The first-line therapy for mild-persistent asthma is:
Low-dose inhaled corticosteroids
Question 12 1 / 1 point
All of the following statements about the Beer’s List are true except:
It is a list of medications or medication classes that should generally be avoided in persons 65 years or older because they are either ineffective or they pose unnecessarily high risk for older persons and a safer alternative is available.
It is derived from the expert opinion of one geriatrician and is not evidence-based.
These criteria have been adopted by the Centers for Medicare and Medicaid Services for regulation of long-term care facilities.
These criteria are directed at the general population of patients over 65 years of age and do not take disease states into consideration.
Question 13 1 / 1 point
Isosorbide dinitrate is prescribed for a patient with chronic stable angina. This drug is administered twice daily, but the schedule is 7 a.m. and 2 p.m. because:
It is a long-acting drug with potential for toxicity.
Nitrate tolerance can develop.
Orthostatic hypotension is a common adverse effect.
It must be taken with milk or food.
Question 14 1 / 1 point
True contraindications to diphtheria, tetanus, and acellular pertussis (DTaP or Tdap) vaccine include:
Fever up to 104oF (40.5oC) after previous DTaP vaccine
Family history of seizures after DTaP vaccine
Anaphylactic reaction with a previous dose
Question 15 1 / 1 point
Gender differences between men and women in pharmacokinetics include:
More rapid gastric emptying so that drugs absorbed in the stomach have less exposure to absorption sites
Higher proportion of body fat so that lipophilic drugs have relatively greater volumes of distribution
Increased levels of bile acids so that drugs metabolized in the intestine have higher concentrations
Slower organ blood flow rates so drugs tend to take longer to be excreted
Question 16 1 / 1 point
Disease states in addition to hypertension in which beta blockade is a compelling indication for the use of beta blockers include:
Question 17 1 / 1 point
Developmental variation in renal function has what impact on prescribing for infants and children?
Lower doses of renally excreted drugs may be prescribed to infants younger than age 6 months.
Higher doses of water soluble drugs may need to be prescribed because of increased renal excretion.
Renal excretion rates have no impact on prescribing.
Parents need to be instructed on whether drugs are renally excreted or not.
Question 18 1 / 1 point
When a pharmacoeconomic analysis looks at two or more treatment alternatives that are considered equal in efficacy and compares the costs of each it is referred to as:
Question 19 1 / 1 point
Allison is an 18-year-old college student with type 1 diabetes. She is on NPH twice daily and Novolog before meals. She usually walks for 40 minutes each evening as part of her exercise regimen. She is beginning a 30-minute swimming class three times a week at 1 p.m. What is important for her to do with this change in routine?
Delay eating the midday meal until after the swimming class.
Increase the morning dose of NPH insulin on days of the swimming class.
Adjust the morning insulin injection so that the peak occurs while swimming.
Check glucose level before, during, and after swimming.
Question 20 0 / 1 point
A woman who is pregnant and has hyperthyroidism is best managed by a specialty team who will most likely treat her with:
Nothing, treatment is best delayed until after her pregnancy ends
Question 21 1 / 1 point
Which of the following is a primary benefit of the use of computerized provider order entry for patient medications?
Reduces time that prescribing drugs takes
Eliminates the need to chart drugs prescribed
Decreases prescribing and transcription errors
Helps keep the number of drugs prescribed to a minimum
Question 22 1 / 1 point
Lisa is a healthy nonpregnant adult woman who recently had a urinary tract infection (UTI). She is asking about drinking cranberry juice to prevent a recurrence of the UTI. The correct answer to give her would be:
Sixteen ounces per day of cranberry juice cocktail will prevent UTIs.
100% cranberry juice or cranberry juice extract may decrease UTIs in some patients.
There is no evidence that cranberry juice helps prevent UTIs.
Cranberry juice only works to prevent UTIs in children.
Question 23 1 / 1 point
Ginseng, which is taken to assist with memory, may potentiate:
Question 24 1 / 1 point
While on testosterone replacement, hemoglobin and hematocrit levels should be monitored. Levels suggestive of excessive erythrocytosis or abuse are:
Hemoglobin 14 g/dl or hematocrit 39%
Hemoglobin 11.5 g/dl or hematocrit 31%
Hemoglobin 13 g/dl or hematocrit 38%
Hemoglobin 17.5 g/dl or hematocrit 54%
Question 25 1 / 1 point
What is the role of calcium supplements when patients take bisphosphonates?
They must be restricted to allow the medication to work.
They must be taken in sufficient amounts to provide foundational elements for bone growth.
They must be taken at the same time as the bisphosphonates.
They only work with bisphosphonates if daily intake is restricted.
Question 26 1 / 1 point
Clinical judgment in prescribing includes:
Factoring in the cost to the patient of the medication prescribed
Always prescribing the newest medication available for the disease process
Handing out drug samples to poor patients
Prescribing all generic medications to cut costs
Question 27 1 / 1 point
The most cost-effective treatment for two or three impetigo lesions on the face is:
Retapamulin (Altabax) ointment
Topical clindamycin solution
Oral amoxicillin/clavulanate (Augmentin)
Question 28 1 / 1 point
Medications are typically started for angina patients when:
The first permanent EKG changes occur
The start of class I or II symptoms
The events trigger a trip to the emergency department
When troponin levels become altered
Question 29 0 / 1 point
Rabi is being prescribed phenytoin for seizures. Monitoring includes assessing:
For phenytoin hypersensitivity syndrome 3 to 8 weeks after starting treatment
For pedal edema throughout therapy
Heart rate at each visit and consider altering therapy if heart rate is less than 60 bpm
For vision changes, such as red-green blindness, at least annually
Question 30 1 / 1 point
Alterations in drug metabolism among Asians may lead to:
Slower metabolism of antidepressants, requiring lower doses
Faster metabolism of neuroleptics, requiring higher doses
Altered metabolism of omeprazole, requiring higher doses
Slower metabolism of alcohol, requiring higher doses
Question 31 1 / 1 point
The dosage of Vitamin B12 to initially treat pernicious anemia is:
Nasal cyanocobalamin 1 gram spray in each nostril daily x 1 week then weekly x 1 month
Vitamin B12 IM monthly
Vitamin B12 1,000 mcg IM daily x 1 week then 1,000 mg IM weekly for a month
Oral cobalamin 1,000 mcg daily
Question 32 1 / 1 point
There is often cross-sensitivity and cross-resistance between penicillins and cephalosporins because:
Renal excretion is similar in both classes of drugs.
When these drug classes are metabolized in the liver they both produce resistant enzymes.
Both drug classes contain a beta-lactam ring that is vulnerable to beta-lactamase-producing organisms.
There is not an issue with cross-resistance between the penicillins and cephalosporins.
Question 33 1 / 1 point
The reason that two MMR vaccines at least a month apart are recommended is:
The second dose of MMR “boosts” the immunity built from the first dose.
Two vaccines 1 month apart is the standard dosing for all live virus vaccines.
If the two MMR vaccine doses are given too close together there is a greater likelihood of severe localized reaction to the vaccine.
Only 95% of patients are fully immunized for measles after the first vaccine, with 99% having immunity after two doses of MMR.
Question 34 1 / 1 point
A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration. This means that the:
Concentration will produce therapeutic effects
Concentration will produce an adverse response
Time between doses must be shortened
Duration of action of the drug is too long
Question 35 1 / 1 point
Why is the consistency of taking paroxetine (Paxil) and never running out of medication more important than with most other selective serotonin reuptake inhibitors (SSRIs)?
It has a shorter half-life and withdrawal syndrome has a faster onset without taper.
It has the longest half-life and the withdrawal syndrome has a faster onset.
It is quasi-addictive in the dopaminergic reward system.
It is the most activating of SSRI medications and will cause the person to have sudden deep sadness.
Question 36 1 / 1 point
Chee is a 15-month-old male whose screening hemoglobin is 10.4 g/dL. Treatment for his anemia would be:
18 mg/day of iron supplementation
6 mg/kg per day of elemental iron
325 mg ferrous sulfate per day
325 mg ferrous sulfate tid
Question 37 1 / 1 point
Education for patients who use an inhaled beta-agonist and an inhaled corticosteroid includes:
Use the inhaled corticosteroid first, followed by the inhaled beta-agonists.
Use the inhaled beta-agonist first, followed by the inhaled corticosteroid.
Increase fluid intake to 3 liters per day.
Avoid use of aspirin or ibuprofen while using inhaled medications.
Question 38 1 / 1 point
According to the U.S. Office of Minority Health, poor health outcomes among African Americans are attributed to:
The belief among African Americans that prayer is more powerful than drugs
Poor compliance on the part of the African American patient
The genetic predisposition for illness found among African Americans
Discrimination, cultural barriers, and lack of access to health care
Question 39 0 / 1 point
Precautions that should be taken when prescribing controlled substances include:
Faxing the prescription for a Schedule II drug directly to the pharmacy
Using tamper-proof paper for all prescriptions written for controlled drugs
Keeping any pre-signed prescription pads in a locked drawer in the clinic
Using only numbers to indicate the amount of drug to be prescribed
Question 40 1 / 1 point
When considering which cholesterol-lowering drug to prescribe, which factor determines the type and intensity of treatment?
Coronary artery disease risk level
Fasting total cholesterol
Question 41 1 / 1 point
Which of the following patients may be treated with a 3-day course of therapy for their urinary tract infection?
Juanita, a 28-year-old pregnant woman
Sally, a 16-year-old healthy adolescent
Jamie, a 24-year-old female
Suzie, a 26-year-old diabetic
Question 42 1 / 1 point
If an adult patient with comorbidities cannot reliably take oral antibiotics to treat pneumonia, an appropriate initial treatment option would be:
IV or IM gentamicin
IV or IM ceftriaxone
Question 43 1 / 1 point
Varenicline (Chantix) may be prescribed for tobacco cessation. Instructions to the patient who is starting varenicline include:
The maximum time varenicline can be used is 12 weeks.
Nausea is a sign of varenicline toxicity and should be reported to the provider.
The starting regimen for varenicline is start taking 1 mg twice a day a week before the quit date.
Neuropsychiatric symptoms may occur.
Question 44 0 / 1 point
Harold, a 42-year-old African American, has moderate persistent asthma. Which of the following asthma medications should be used cautiously, if at all?
Betamethasone, an inhaled corticosteroid
Salmeterol, an inhaled long-acting beta-agonist
Albuterol, a short-acting beta-agonist
Montelukast, a leukotriene modifier
Question 45 1 / 1 point
Absolute contraindications that clinicians must consider when initiating estrogen therapy include:
Undiagnosed dysfunctional uterine bleeding
Deep vein or arterial thromboemboli within the prior year
Both a. and b.
All of the above
Question 46 1 / 1 point
Several classes of drugs have interactions with cholinergic blockers. Which of the following is true about these interactions?
Drugs with a narrow therapeutic range given orally may not stay in the GI tract long enough to produce an action.
Additive antimuscarinic effects may occur with antihistamines.
Cholinergic blockers may decrease the sedative effects of hypnotics.
Cholinergic blockers are contraindicated with antipsychotics.
Question 47 1 / 1 point
Leonard is completing a 6-month regimen to treat tuberculosis (TB). Monitoring of a patient on TB therapy includes:
Monthly sputum cultures
Monthly chest x-ray
Bronchoscopy every 3 months
All of the above
Question 48 1 / 1 point
The action of “gliptins” is different from other antidiabetic agents because they:
Have a low risk for hypoglycemia
Are not associated with weight gain
Close ATP-dependent potassium channels in the beta cell
Act on the incretin system to indirectly increase insulin production
Question 49 1 / 1 point
Laboratory values are actually different for TSH when screening for thyroid issues and when used for medication management. Which of the follow holds true?
Screening TSH has a wider range of normal values 0.02-5.0; therapeutic levels need to remain above 5.0.
Screening values are much narrower than the acceptable range used to keep a person stable on hormone replacement.
Therapeutic values are kept between 0.05 and 3.0 ideally. Screening values are considered acceptable up to 10.
Screening values are between 5 and 10, and therapeutic values are greater than 10.
Question 50 1 / 1 point
Azithromycin dosing requires that the first day’s dosage be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose:
Rapidly achieves drug levels in the therapeutic range
Requires four- to five-half-lives to attain
Is influenced by renal function
Is directly related to the drug circulating to the target tissues
Question 51 1 / 1 point
Conjunctivitis in a child that is accompanied by acute otitis media is treated with:
Sulfacetamide 10% ophthalmic solution (Bleph-10)
Bacitracin/polymyxin B (Polysporin) ophthalmic drops
Ciprofloxacin (Ciloxan) ophthalmic drops
High-dose oral amoxicillin
Question 52 1 / 1 point
To improve actual effectiveness of oral contraceptives women should be educated regarding:
Use of a back-up method if they have vomiting or diarrhea during a pill packet
Doubling pills if they have diarrhea during the middle of a pill pack
The fact that they will have a normal menstrual cycle if they miss two pills
The fact that mid-cycle spotting is not normal and the provider should be contacted immediately
Question 53 1 / 1 point
An acceptable first-line treatment for peptic ulcer disease with positive H. pylori test is:
Histamine2 receptor antagonists for 4 to 8 weeks
Proton pump inhibitor bid for 12 weeks until healing is complete
Proton pump inhibitor bid plus clarithromycin plus amoxicillin for 14 days
Proton pump inhibitor bid and levofloxacin for 14 days
Question 54 1 / 1 point
Larry is taking allopurinol to prevent gout. Monitoring of a patient who is taking allopurinol includes:
Complete blood count
BUN, creatinine, and creatinine clearance
Question 55 1 / 1 point
When discussing with a patient the different start methods used for oral combined contraceptives, the advantage of a Sunday start over the other start methods is:
Immediate protection against pregnancy the first week of using the pill
No back-up method is needed when starting
Menses occur during the week
They can start the pill on the Sunday after the office visit
Question 56 1 / 1 point
Sadie is a 90-year-old patient who requires a new prescription. What changes in drug distribution with aging would influence prescribing for Sadie?
Increased volume of distribution
Decreased lipid solubility
Decreased plasma proteins
Increased muscle-to-fat ratio
Question 57 1 / 1 point
Rose is a 3-year-old patient with an upper respiratory infection (URI). Treatment for her URI would include:
Nasal saline spray
Question 58 1 / 1 point
Instructions for the use of nicotine gum include:
Chew the gum quickly to get a peak effect.
The gum should be “parked” in the buccal space between chewing.
Acidic drinks such as coffee help with the absorption of the nicotine.
The highest abstinence rates occur if the patient chews the gum when he or she is having cravings.
Question 59 0 / 1 point
Howard is a 72-year-old male who occasionally takes diphenhydramine for his seasonal allergies. Monitoring for this patient taking diphenhydramine would include assessing for:
Question 60 0 / 1 point
Vicky, age 56 years, comes to the clinic requesting a refill of her Fiorinal (aspirin and butalbital) that she takes for migraines. She has been taking this medication for over 2 years for migraines and states one dose usually works to abort her migraine. What is the best care for her?
Switch her to sumatriptan (Imitrex) to treat her migraines.
Assess how often she is using Fiorinal and refill her medication.
Switch her to a beta blocker such as propranolol to prevent her migraine.
Request she return to the original prescriber of Fiorinal as you do not prescribe butalbital for migraines.
Question 61 1 / 1 point
Drugs that have a significant first-pass effect:
Must be given by the enteral (oral) route only
Bypass the hepatic circulation
Are rapidly metabolized by the liver and may have little if any desired action
Are converted by the liver to more active and fat-soluble forms
Question 62 1 / 1 point
First-line therapy for treating topical fungal infections such as tinea corporis (ringworm) or tinea pedis (athlete’s foot) would be:
OTC topical azole (clotrimazole, miconazole)
Oral griseofulvin microsize
Nystatin cream or ointment
Question 63 1 / 1 point
A client asks the NP about the differences in drug effects between men and women. What is known about the differences between the pharmacokinetics of men and women?
Body temperature varies between men and women.
Muscle mass is greater in women.
Percentage of fat differs between genders.
Proven subjective factors exist between the genders.
Question 64 1 / 1 point
Opiates are used mainly to treat moderate to severe pain. Which of the following is NOT true about these drugs?
All opiates are scheduled drugs which require a DEA license to prescribe.
Opiates stimulate only mu receptors for the control of pain.
Most of the adverse effects of opiates are related to mu receptor stimulation.
Naloxone is an antagonist to opiates.
Question 65 1 / 1 point
A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is angioedema. Which of the following statements is true about this adverse response?
Swelling of the tongue or hoarseness are the most common symptoms.
It appears to be related to the decrease in aldosterone production.
Presence of a dry, hacky cough indicates a high risk for this adverse response.
Because it takes time to build up a blood level, it occurs after being on the drug for about 1 week.
Question 66 1 / 1 point
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber include:
Nurses know more about Pharmacology than other prescribers because they take it both in their basic nursing program and in their APRN program.
Nurses care for the patient from a holistic approach and include the patient in decision making regarding their care.
APRNs are less likely to prescribe narcotics and other controlled substances.
APRNs are able to prescribe independently in all states, whereas a physician’s assistant needs to have a physician supervising their practice.
Question 67 1 / 1 point
Education of women who are being treated with ophthalmic antibiotics for conjunctivitis includes:
Throwing away eye makeup and purchasing new
Redness and intense burning is normal with ophthalmic antibiotics
When applying eye ointment, set the tip of the tube on the lower lid and squeeze in inch
Use a cotton swab to apply ointment, spreading the ointment all over the lid and in the conjunctival sac
Question 68 1 / 1 point
When determining drug treatment the NP prescriber should:
Always use evidence-based guidelines
Individualize the drug choice for the specific patient
Rely on his or her experience when prescribing for complex patients
Use the newest drug on the market for the condition being treated
Question 69 1 / 1 point
Class I recommendations for stage A heart failure include:
Aerobic exercise within tolerance levels to prevent the development of heart failure
Reduction of sodium intake to less than 2,000 mg/day to prevent fluid retention
Beta blockers for all patients regardless of cardiac history
Treatment of thyroid disorders, especially if they are associated with Tachyarrhythmias
Question 70 1 / 1 point
Male patients who should not be prescribed phosphodiesterase type 5 (PDE-5) inhibitors include:
Those who have had an acute myocardial infarction in the past 6 months
Patients who are deaf
Patients under age 60 years of age
Question 71 1 / 1 point
The first-line drug choice for a previously healthy adult patient diagnosed with community-acquired pneumonia would be:
Question 72 1 / 1 point
If a patient with symptoms of gastroesophageal reflux disease states that he has been self-treating at home with OTC ranitidine daily, the appropriate treatment would be:
Prokinetic (metoclopramide) for 4 to 8 weeks
Proton pump inhibitor (omeprazole) for 12 weeks
Histamine2 receptor antagonist (ranitidine) for 4 to 8 weeks
Cytoprotective drug (misoprostol) for 2 weeks
Question 73 1 / 1 point
Patients who are prescribed exogenous androgens need to be warned that decreased libido:
Is an unusual side effect of androgens and should be reported to the provider
Is treated with increased doses of androgens, so the patient should let the provider know if he is having problems
May be a sign of early prostate cancer and he should make an appointment for a prostate screening exam
May occur with androgen therapy
Question 74 1 / 1 point
Which diuretic agents typically do not need potassium supplementation?
The loop diuretics
The thiazide diuretics
The aldosterone inhibitors
They all need supplementation
Question 75 0 / 1 point
Jim is being treated for hypertension. Because he has a history of heart attack, the drug chosen is atenolol. Beta blockers treat hypertension by:
Increasing heart rate to improve cardiac output
Reducing vascular smooth muscle tone
Increasing aldosterone-mediated volume activity
Reducing aqueous humor production
Question 76 1 / 1 point
Patient education regarding taking iron replacements includes:
Doubling the dose if they miss a dose to maintain therapeutic levels
Taking the iron with milk or crackers if it upsets their stomach
Iron is best taken on an empty stomach with juice
Antacids such as Tums may help the upset stomach caused by iron therapy
Question 77 1 / 1 point
Patient education for a patient who is prescribed antibiotics for sinusitis includes:
Use of nasal saline washes
Use of inhaled corticosteroids
Avoiding the use of ibuprofen while ill
Use of laxatives to treat constipation
Question 78 1 / 1 point
Patients who are treated with greater than 100 grams per week of topical calcipotriene for psoriasis need to be monitored for:
High vitamin D levels
Question 79 1 / 1 point
Sook has been prescribed gabapentin to treat neuropathic pain and is complaining of feeling depressed and having “strange” thoughts. The appropriate initial action would be:
Increase her dose
Assess for suicidal ideation
Discontinue the medication immediately
Decrease her dose to half then slowly titrate up the dose
Question 80 1 / 1 point
Nonadherence is especially common in drugs that treat asymptomatic conditions, such as hypertension. One way to reduce the likelihood of nonadherence to these drugs is to prescribe a drug that:
Has a short half-life so that missing one dose has limited effect
Requires several dosage titrations so that missed doses can be replaced with lower doses to keep costs down
Has a tolerability profile with fewer of the adverse effects that are considered “irritating,” such as nausea and dizziness
Must be taken no more than twice a day
Question 81 1 / 1 point
Which the following persons should not have a statin medication ordered?
Someone with 3 first- or second-degree family members with history of muscle issues when started on statins
Someone with high lipids, but low BMI
Premenopausal woman with recent history of hysterectomy
Prediabetic male with known metabolic syndrome
Question 82 1 / 1 point
The Combat Methamphetamine Epidemic Act, which is part of the 2006 U.S. Patriot Act:
Requires all providers to screen their patients for methamphetamine use
Restricts the prescribing of amphetamines to U.S. citizens
Requires a prescription be written for all methamphetamine precursors in all states
Restricts the sales of drugs that contain methamphetamine precursors, including a daily and 30-day limit on sales
Question 83 0 / 1 point
Monitoring for patients who are on long-term antifungal therapy with ketoconazole includes:
BUN and creatinine
White blood cell count
AST, ALT, alkaline phosphatase, and bilirubin
Question 84 0 / 1 point
Which of the following holds true for the pharmacokinetics of women?
Gastric emptying is faster than that of men.
Organ blood flow is the same as that of men.
Evidence is strong concerning renal differences in elimination.
Medications that involve binding globulins are impacted by estrogen levels.
Question 85 0 / 1 point
Henry is 82 years old and takes two aspirin every morning to treat the arthritis pain in his back. He states the aspirin helps him to “get going” each day. Lately he has had some heartburn from the aspirin. After ruling out an acute GI bleed, what would be an appropriate course of treatment for Henry?
Add an H2 blocker such as ranitidine to his therapy.
Discontinue the aspirin and switch him to Vicodin for the pain.
Decrease the aspirin dose to one tablet daily.
Have Henry take an antacid 15 minutes before taking the aspirin each day.
Question 86 1 / 1 point
When prescribing a tetracycline or quinolone antibiotic it is critical to instruct the patient:
Not to take their regularly prescribed medications while on these antibiotics
Regarding the need for lots of acidic foods and juices, such as orange juice, to enhance absorption
Not to take antacids while on these medications, as the antacid decreases absorption
That there are no drug interactions with these antibiotics
Question 87 1 / 1 point
A provider may consider testing for CYP2D6 variants prior to starting tamoxifen for breast cancer to:
Ensure the patient will not have increased adverse drug reactions to the tamoxifen
Identify potential drug-drug interactions that may occur with tamoxifen
Reduce the likelihood of therapeutic failure with tamoxifen treatment
Identify poor metabolizers of tamoxifen
Question 88 1 / 1 point
IV forms of bisphosphonates are used for all the following except:
Severe gastric irritation with oral forms
Known cancer mets into the bone
Persons with advancing renal dysfunction
Progression of bone loss on oral formulations
Question 89 1 / 1 point
The New York Heart Association and the Canadian Cardiovascular Society have described grading criteria for levels of angina. Angina that occurs with unusually strenuous activity or on walking or climbing stair after meals is class:
Question 90 1 / 1 point
ACE inhibitors are contraindicated in pregnancy. While treatment of heart failure during pregnancy is best done by a specialist, which of the following drug classes is considered to be safe, at least in the later parts of pregnancy?
Question 91 1 / 1 point
The study of the part of the U.S. economy devoted to drug use
The study of the impact of prescription drug costs on the overall economy
The analysis of the costs and consequences of any health-care-related treatment or service
The analysis of the clinical efficacy of the drug
Question 92 1 / 1 point
Goals when treating tuberculosis include:
Completion of recommended therapy
Negative purified protein derivative at the end of therapy
Completely normal chest x-ray
All of the above
Question 93 1 / 1 point
Elena Vasquez’s primary language is Spanish, and she speaks very limited English. Which technique would be appropriate to use in teaching her about a new drug you have just prescribed?
Use correct medical terminology because Spanish has a Latin base.
Use a family member who speaks more English to act as an interpreter.
Use a professional interpreter or a reliable staff member who can act as an interpreter.
Use careful, detailed explanations.
Question 94 1 / 1 point
Which of the following statements is true about acute pain?
Somatic pain comes from body surfaces and is only sharp and well-localized.
Visceral pain comes from the internal organs and is most responsive to acetaminophen and opiates.
Referred pain is present in a distant site for the pain source and is based on activation of the same spinal segment as the actual pain site.
Acute neuropathic pain is caused by lack of blood supply to the nerves in a given area.
Question 95 1 / 1 point
The role of the NP in the use of herbal medication is to:
Maintain competence in the prescribing of common herbal remedies
Recommend common over-the-counter herbs to patients
Educate patients and guide them to appropriate sources of care
Encourage patients to not use herbal therapy due to the documented dangers
Question 96 1 / 1 point
Being competent in the use of information technology in clinical practice is expected in professional nurses. Advanced practice competence includes the ability to:
Search for information using the most common search engines
Serve as content experts in developing, implementing, and evaluating information Systems
Write programs to assure the integrity of health information
Use information technology to prescribe drugs
Question 97 0 / 1 point
Sally has been prescribed aspirin 320 mg per day for her atrial fibrillation. She also takes aspirin four or more times a day for arthritis pain.What are the symptoms of aspirin toxicity for which she would need to be evaluated?
Question 98 1 / 1 point
Nurse practitioner prescriptive authority is regulated by:
The National Council of State Boards of Nursing
The U.S. Drug Enforcement Administration
The State Board of Nursing for each state
The State Board of Pharmacy
Question 99 1 / 1 point
An Investigational New Drug is filed with the U.S. Food and Drug Administration:
When the manufacturer has completed phase III trials
When a new drug is discovered
Prior to animal testing of any new drug entity
Prior to human testing of any new drug entity
Question 100 1 / 1 point
Preventative therapy for cluster headaches includes:
Massage or relaxation therapy
Ergotamine nightly before bed
Intranasal lidocaine four times a day during “clusters” of headaches
Propranolol (Inderal) daily
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