Difficult-to-Treat
Hyperthyroidism: A Case Study
Pg 1-7
Authors: Earn H. Gan, MBChB, MRCP; Simon H. S. Pearce, MD, FRCP
Source: Endocrinology and Diabetes: Case Studies, Questions and Commentaries, R. Ajjan,
S.M. Orme (eds.), 2015, DOI: 10.1007/978-1-4471-2789-5_1, © Springer-Verlag London
Abstract:
This case study presents a 31-year-old female with difficult-to-treat hyperthyroidism and
mild thyroid eye disease. The case explores questions related to this condition, covering
clinical signs, appropriate investigations, management, and follow-up. The patient's journey
underscores the heterogeneity of hyperthyroidism and the challenges faced in treatment.
Despite conventional anti-thyroid drug therapy, the patient's condition worsened, leading to
eventual total thyroidectomy. The case also delves into the management options for
aggressive Graves' disease.
Keywords:
Hyperthyroidism, Thyrotoxicosis, Thyroid autoantibody, Antithyroid medication,
Radioiodine therapy
Introduction: Hyperthyroidism, a disorder caused by excessive thyroid hormone production,
presents with a range of symptoms affecting multiple systems. Although antithyroid drugs,
radioiodine therapy, and total thyroidectomy are available treatment options, managing
refractory cases can be challenging.
Case Presentation:
Hyperthyroidism: A Case Study
Pg 1-7
Authors: Earn H. Gan, MBChB, MRCP; Simon H. S. Pearce, MD, FRCP
Source: Endocrinology and Diabetes: Case Studies, Questions and Commentaries, R. Ajjan,
S.M. Orme (eds.), 2015, DOI: 10.1007/978-1-4471-2789-5_1, © Springer-Verlag London
Abstract:
This case study presents a 31-year-old female with difficult-to-treat hyperthyroidism and
mild thyroid eye disease. The case explores questions related to this condition, covering
clinical signs, appropriate investigations, management, and follow-up. The patient's journey
underscores the heterogeneity of hyperthyroidism and the challenges faced in treatment.
Despite conventional anti-thyroid drug therapy, the patient's condition worsened, leading to
eventual total thyroidectomy. The case also delves into the management options for
aggressive Graves' disease.
Keywords:
Hyperthyroidism, Thyrotoxicosis, Thyroid autoantibody, Antithyroid medication,
Radioiodine therapy
Introduction: Hyperthyroidism, a disorder caused by excessive thyroid hormone production,
presents with a range of symptoms affecting multiple systems. Although antithyroid drugs,
radioiodine therapy, and total thyroidectomy are available treatment options, managing
refractory cases can be challenging.
Case Presentation:
