MSN 570 Advance Patho| Questions with complete Answers

MI Correct Answer: Death of myocardium from sudden blockage of coronary artery blood flow What causes cell death in MI? Correct Answer: unstable plaque breaks off, triggering platelet aggregation, coagulation cascade and thrombus formation. continued no blood flow in 10 seconds ischemia, 20 minutes cell die What consequence of cell death leads to CP? Correct Answer: hypoxia as cannot meet cell demand for oxygen How is MI diagnosed Correct Answer: EKG (STEMI) or elevated Troponin (non-STEMI) What might you find in blood consistent with MI? Correct Answer: elevated CK MB, Troponin Where does CK MB and Troponin come from? Correct Answer: Release of lysosomal enzymes; CK MB detected after myocardial necrosis, Troponin released from damaged heart muscle 3 mechanism of cell injury related to reperfussion injury Correct Answer: ischemia, necrosis, reperfussion l/t RAS define reperfussion injury Correct Answer: injury that occurs after oxygen is reintroduced to tissue perfusion how does inflammatory process contribute to reperfussion injury? Correct Answer: as oxygen is reintroduced it comes in contact with damaged proteins triggering inflammatory response how does oxidative process contribute to RI? Correct Answer: RAS causes impairment of cell membrane and pro-apotptoic cells release. making cell unstable what is primary Hypertension? Correct Answer: Essential or idiopathic, elevated BP without an identified cause, accounts for 90 - 95% of all cases of hypertension? what is secondary hyperten