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unit 12a; disease and infection

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part 2 of pass criteria for 12a

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Non-infectious diseases
Non-infectious diseases cannot be transmitted from one person to another since they are not caused by
pathogens. However, these diseases are brought on by things like genes, malnutrition, environment, and
lifestyle. Heart disease, asbestos, cystic fibrosis, and Alzheimer's disease are a few examples of non-
infectious disorders.

Dietary
Coronary heart disease
Coronary heart disease is a condition where the coronary arteries constrict or get blocked (blood vessels
that carry blood and oxygen to the heart). Atherosclerosis is typically the cause of coronary heart
disease. It involves a build-up of fatty material and plaque inside the coronary arteries. The condition
may result in heart attacks, shortness of breath while exercising, and chest pain. These symptoms are
due to reduced blood flow or even a complete blockage of blood flow which causes the heart attack. A
family history of coronary heart disease before the age of 50, advanced age, tobacco use, high blood
pressure, high cholesterol, diabetes, inactivity, and obesity all raise the risk of developing coronary heart
disease. Coronary heart disease is more likely to develop when there is too much salt in a poor diet.
Consuming foods that are high in cholesterol and saturated fats increases the risks as well. Foods heavy
in saturated fats including butter, cream, sausages, and cakes/biscuits should all be avoided.

Depression has been linked to a variety of aspects of coronary artery disease, including arrhythmias,
myocardial infarction, heart failure, and sudden death. Mechanisms underlying depression and
cardiovascular disease have been proposed to include hypothalamic-pituitary-adrenal dysregulation,
decreased heart rate variability, altered blood platelet function, and noncompliance with medical
treatments.

Environmental
Asbestos
Asbestosis, a persistent lung ailment, can be caused by inhaling asbestos fibres. Long-term exposure to
these fibres can cause lung tissue damage and shortness of breath. Alveoli play an important role in
both delivering oxygen from the air into your bloodstream and eliminating carbon dioxide from your
bloodstream. Asbestosis causes scarring of the lung tissues and thickening of the tissue between the
alveoli, resulting in inefficient oxygen transport into the bloodstream. Asbestosis symptoms range from
mild to severe and usually appear years after the initial exposure. Shortness of breath, a persistent dry
cough, tightness in the chest, dry and crackling sounds in the lungs when you breathe in, as well as
clubbing, a condition where the fingertips and toes appear broader and rounder than normal, are some
of the indications and symptoms of asbestosis. Scarred lung tissue also leads to the lungs becoming stiff,
therefore resulting in a tight feeling in the chest/difficulty breathing and the lungs not being able to
contract and expand properly.

Long-term asbestos exposure puts people at a high risk of developing asbestosis. Asbestos miners,
aircraft mechanics, construction crews, electricians, and railroad/shipyard workers all work with
asbestos-containing materials. Even if you do not work with asbestos, you may be exposed if you live
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