Neuropharm Sleep (A+ Graded Already)

ascending reticular activating system correct answers all feeds into thalamus -desynchronizes or synchronizes the EEG activity What tells the cortex whether or not to respond to activity? correct answers thalamus LC sleep correct answers -Release norepinephrine to arouse various areas of the cortex and increase wakefulness -Usually dormant while asleep -decrease in APs in area while asleep Raphe sleep correct answers -Release serotonin to arouse various areas of the cortex and increase wakefulness -Usually dormant while asleep -decrease in APs pontine tegmentum correct answers Stimulating pons leads to wakefulness -lesions in pons make cats sleepy -Contains acetylcholine neurons that project to the forebrain Ventrolateral preoptic nucleus (VLPO) correct answers biggest sleep promoting brain region -Comprised of GABAergic inhibitory neurons -Oppose the RAS through reciprocal connections -Decreasing the temperature and metabolic rate -Activation of this area initiates sleep onset -Inhibits acetylcholine-releasing cells in the basal forebrain to stimulate neurons responsible for wakefulness and arousal lateral hypothalamus correct answers -Comprised of orexin-containing neurons -Activation promotes wakefulness -Stimulates acetylcholine-releasing cells in the basal forebrain to stimulate neurons responsible for wakefulness and arousal - our appetite drive is highest when we are most active TMN correct answers -Comprised of histamine-containing neurons -Regulates the activity of the cortex and the VLPO Suprachiasmatic nucleus correct answers -Located above the optic chiasm (supra to the chiasm) -Detects light stimuli to help regulate circadian and sleep-wake cycling -Pacemaker hypothalamic areas involved in sleep and arousal correct answers TMN, lateral hypothalamus, suprachiasmatic nucleus, VLPO basal forebrain correct answers -Anterior to the hypothalamus