PHARMACOLOGY EXAM 1- RASMUSSEN|UPDATED&VERIFIED|100% SOLVED|GUARANTEED SUCCESS

Drugs that PRODUCE a response agonist Drug that PREVENT or block a response antagonist Therapeutic WINDOW is what? level of the drug between minimal effective concentration in the plasma for obtaining desired drug response and the minimal toxic concentration The time it takes for one half of the drug concentration to be eliminated from the body is called? half life what is a patient on two highly protein bound drugs at risk for? accumulation and toxicity a decreased responsiveness over the course of therapy, which may lead to the need to increase dosages to attain the same effect tolerance what is it called for drugs to share many common features classification or class what makes drugs fit into the same "Class" -related by chemical structure -work in the same way -used for the same purpose another name for antagonist adrenergic blocker who do you NOT give antagonist or adrenergic blocker to? asthma client Beta Blockers commonly seen in what clients? hypertension antagononist suffix LOL antagonist S/S decreased heart rate rest and digest bronchospasm agonist S/S increased heart rate fight or flight vasoconstriction increased blood sugar Before administering antagonist what do you check Heart rate Blood Pressure Cholinergic salivate lacrimation urinate deficate decreased weight Anticholinergic Cant see Cant pee Cant spit Cant poop increased heart rate what type of drug is Reglan? Cholinergic how do you treat cholinergic crisis atropine cholinergic crisis S/S flushing sweating nausea abd cramping anticholinergic drugs are contradicted in who? -coronary artery disease (Increase heart rate) -GI obstruction (constipates) -supraventricular tachycardia (increased heart rate) CNS stimulant drugs are contradicted in who? -coronary artery disease (cause vasoconstriction=heart attack) -Hypertension (additive hypertension=stroke) Hemorrhagic stroke -increased B/P -increased heart rate -increased respiratory rate -unresponsive to deep pain Anorexiants can leas to what? 16X greater for stroke Most common side effects of Ritalin -irratability -insomnia -weight loss -decreased appetite Benzodiazapines increase activity to what neurotransmitter GABA Reversal to benzodiazapines flumazenil Ambien Side effects -sedative/hypnotic -suicidal ideation -dependence -abnormal behavior Drug of choice for treating status epilepticus diazepams Dilantin can do what? -cause gum disease -treat seizures -cause high blood pressure -cause birth defects -decrease effectiveness of anticoagulants When a client is on Dilantin what are some nursing interventions? -monitor for narrow therapeutic index (frequent blood test) -take as prescribed -oral care -teach pt to use barrier contraceptives along with oral