MSN 570 Advance Patho Midterm Study Guide with Complete Questions and Answers 100% Accurate
MI - ANSWER-Death of myocardium from sudden blockage of coronary artery blood flow What causes cell death in MI? - ANSWER-unstable plaque breaks off, triggering platelet aggregation, coagulation cascade and thrombus formation. continued no blood flow in 10 seconds ischemia, 20 minutes cell die What consequence of cell death leads to CP? - ANSWER-hypoxia as cannot meet cell demand for oxygen How is MI diagnosed - ANSWER-EKG (STEMI) or elevated Troponin (non-STEMI) What might you find in blood consistent with MI? - ANSWER-elevated CK MB, Troponin Where does CK MB and Troponin come from? - ANSWER-Release of lysosomal enzymes; CK MB detected after myocardial necrosis, Troponin released from damaged heart muscle 3 mechanism of cell injury related to reperfussion injury - ANSWER-ischemia, necrosis, reperfussion l/t RAS define reperfussion injury - ANSWER-injury that occurs after oxygen is reintroduced to tissue perfusion how does inflammatory process contribute to reperfussion injury? - ANSWER-as oxygen is reintroduced it comes in contact with damaged proteins triggering inflammatory response
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