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Viral Hepatitis - Summary Notes

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A comprehensive, yet concise summary of the Viral Hepatitis topic in Medicine/ Surgery, presented in a colourful and digestible format. Includes all relevant information on the topic summarised, collated from multiple resources including lectures, textbooks, and guidelines. All my notes/ summaries use a consistent colour scheme, style, and structure to help you remember their contents.

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Uploaded on
May 31, 2023
Number of pages
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Written in
2022/2023
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Summary

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·


self-limiting -
Viral
no treatmentrequired, just
Hepatitis supportive.
HAV SEROLOGY


·
Vaccine available for all types exceptHEV.
Chronic Hepatitis B, C, D only.
· =




Acute Hepatitis Symptoms: asymptomatic
·
-



-




Hepatic cause of Jaundice.
organomegaly
-




Liver Failure.
-




Fever, vomiting. Risk Factors: contaminated
A
- -


nausea,
-


IV
Drug use food/water
Route of spread:Faeco-oral (contact, food, blood) Homo. Travel
-
· -



men


high prevelance in Asia, Africa. S. America.
·




in these countries, children are infected
early and are
asymptomatic.
if immunised,
not
mainly travelers, IV
drug users, and homo. men become infected (RFs).
chronic infection resolves and person is immunised.
·
no
-




Incubation period 2-6 weeks.
·




Investigations:HAV-Igm tive
currently infected, HAV-19Gtive resolved/immunised,
·
- -




present in stool once incubated/symptomatic, raised transaminases.

B Route of spread:blood. Most resolve, but -18% become chronic carriers.
· ·




Incubation period 1-6 months.
·




Investigations: AbsAg tive
during incubation active infection.
· -
-




-




HbsAg tive 6 months carrier status.-




Anti-HBC
Antibody tive pastinfection.
-
-




-


Anti-HBs
Antibody tive -
vaccinated.


Route of spread:blood.
C
·




most become chronic carriers,
·




and develop Liver Cirrhosis/Cancer.
HB SEROLOGY
Investigations:Anti-HDV Antibody tive pastinfection.
·
-




Spread:blood.
D. Route of
·


Only HBV Chronic carriers can
develop HDV.

Investigations:Anti-HDV Antibody tive,
·




and by extention HBsAg Hive.




E
-




·
Route of spread:Facco-oral (mostly contaminated water, uncooked pork). HEV SEROLOGY

high prevelance Asia, Africa.
in
·




4 Genotypes:Developing countries HEV1/2. Developed countries HEV 3/4.
·
=
=




Incubation period 2-6 weeks.
·




Investigations:HEV-Igm tive
currently infected, HEV-19Gttive resolved/ immunised,
·
- -




present in stool once incubated/symptomatic, raised transaminases.
·

no chronic infection -
resolves and person is immunised, except immunosuppressed individuals.

Only immunisation vaccine.
without
·

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