CSO 2023 Exam Questions with Complete Solutions

CSO 2023 Exam Questions with Complete Solutions Hormone Therapy - CORRECT ANSWERS Used to treat hormone sensitive cancers. Stops or reduces the body's ability to produce hormones. Also, substitutes chemically similar agents for the active hormones that cannot be used by the tumor. Ex: SERMS, AIs, Progesterones, Antiandrogens, LHRH. Immunomodulatory Drugs - CORRECT ANSWERS Inhibit anti-inflammatory cytokines and exert anti-angiogenic properties. Ex: Revlimid, Thaudomide Adjuvant Therapy - CORRECT ANSWERS The use of additional cancer treatment given after the primary therapy. Ex: chemo after lobectomy Definitive Therapy - CORRECT ANSWERS Prescribed treatment modality with or without additional treatment Neoadjuvant Therapy - CORRECT ANSWERS The use of one or more treatment modalities given before the primary treatment. Biotherapy - CORRECT ANSWERS Treatment to boost or restore the ability of the immune system to fight cancer by inducing, enhancing, or suppressing the immune system response. Also called immunotherapy. Monoclonal Antibodies - CORRECT ANSWERS Therapies that signal external cellular pathway targets which activate pathways inside. Disrupts cell function and causes cell apoptosis. Protein Targeted Therapies - CORRECT ANSWERS Therapies the signal internal cellular pathway that targets proteins. Ex: TKIs, MTOR inhibitor, Proteasome Inhibitor. Angiogenesis Inhibitor - CORRECT ANSWERS Hinder the formation of new blood vessels in primary tumors thus preventing their growth, invasion, and spread. Cytokines - CORRECT ANSWERS Stimulate broad base immune response as opposed to generating a targeted response to specific tumor antigen. Low Risk of Emesis Chemo - CORRECT ANSWERS Bleomycin Busulfan Fludarabine Vinblastine Vincristine Vinorelbine Bevacizumab Anti-Emetic Drugs - CORRECT ANSWERS 1. Serotonin 5-HT3 (zofran, dolasetron, granisetron, palonsetron) 2. Dexamethasone (corticosteroid) 3. Aprepitant (NK1 receptor antagonist) Rezonic (casopitant) or Emend (aprepitant) Chemo that damages GI Tract - CORRECT ANSWERS Methotrexate Melphalan Irinotecan Fluorouracil High Risk of Emesis Chemo - CORRECT ANSWERS Cisplatin Mechlorthamine Cyclophosphamide Carmustine Dacarbazine Moderate Risk of Emesis Chemo - CORRECT ANSWERS Oxaliplatin Cytarabine Carboplatin Ifosfamide Cyclophosphamide Doxorubicin Daurorubicin Epirubicin Idarubicin Irinotecan