LANCASTER UNIVERSITY
2014 EXAMINATIONS
Second Year
BIOMEDICAL & LIFE SCIENCES
Paper A1 (BIOL201) (3 hours)
___________________________________________________________
Answer ALL parts of Section A in one answer booklet. Answer ONE question from Section B
and ONE question from Section C in 2 separate answer booklets. All parts of Section A are
equally weighted. Sections A, B and C also carry equal weighting.
Section A - BIOL201 Biochemistry (answer all five questions)
1. How does epinephrine activate hormone-sensitive triacylglycerol
lipase?
2. How do cellular energy levels control glycolysis and gluconeogenesis?
3. Produce a diagram to illustrate the complete metabolism of pyruvate to CO 2 in a
typical mammalian cell.
4. Give an account of an experiment which has confirmed the rotation of the γ subunit
relative to the β subunits in ATP synthase.
5. What is an isoenzyme? Give one example of an isoenzyme pair and describe briefly
how biochemical differences between each isoenzyme from this pair contribute
usefully to tissue-specific metabolism in mammals.
Section B - BIOL201 Biochemistry (answer one question only)
6. Describe the synthesis of saturated fatty acids.
7. Discuss the role of hormones in the regulation of the metabolic pathways involved in
glucose homeostasis.
8. Discuss how a variety of experimental approaches can be used to inform an
understanding of enzyme structure, activity, or regulation.
Please Turn Over
2014 EXAMINATIONS
Second Year
BIOMEDICAL & LIFE SCIENCES
Paper A1 (BIOL201) (3 hours)
___________________________________________________________
Answer ALL parts of Section A in one answer booklet. Answer ONE question from Section B
and ONE question from Section C in 2 separate answer booklets. All parts of Section A are
equally weighted. Sections A, B and C also carry equal weighting.
Section A - BIOL201 Biochemistry (answer all five questions)
1. How does epinephrine activate hormone-sensitive triacylglycerol
lipase?
2. How do cellular energy levels control glycolysis and gluconeogenesis?
3. Produce a diagram to illustrate the complete metabolism of pyruvate to CO 2 in a
typical mammalian cell.
4. Give an account of an experiment which has confirmed the rotation of the γ subunit
relative to the β subunits in ATP synthase.
5. What is an isoenzyme? Give one example of an isoenzyme pair and describe briefly
how biochemical differences between each isoenzyme from this pair contribute
usefully to tissue-specific metabolism in mammals.
Section B - BIOL201 Biochemistry (answer one question only)
6. Describe the synthesis of saturated fatty acids.
7. Discuss the role of hormones in the regulation of the metabolic pathways involved in
glucose homeostasis.
8. Discuss how a variety of experimental approaches can be used to inform an
understanding of enzyme structure, activity, or regulation.
Please Turn Over
