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Samenvatting H2: techieken

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April 16, 2023
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Written in
2022/2023
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2. TECHNIEKEN OM HERSENFUNCTIES TE
BESTUDEREN


2.1 INLEIDING


Technieken bezitten elk specifieke
 Spatiale resolutie
 Temporele resolutie




1

, 2.2 LETSELSTUDIES


Laesies postmortem of dmv beeldvorming (CT, MRI) correleren aan functieverlies
bv. patiënt H.M.  bilaterale mesiotemporale letsels
bv. Leborgne  Broca-afasie
bv. Phineas Gage  frontale schade




Experimentele letsels bij proefdieren:
 Resectie
 Hitteletsel
 MPTP
 …


Tijdelijke en reversibele (in)activatie door
 Injectie farmacologische agentia
Ø Muscimol: GABAA-agonist
Ø Bicuculline: GABAA-antagonist
 Koeling




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