ATI Pharmacology (2019) latest study guide updated on 2023

ATI Pharmacology (2019) latest study guide updated on 2023 1. benzodiazepines end in: -ze, -zo-, -pam 2. indications for benzo's (5): anxiety, seizures, muscle spasms, alcohol with- drawal, induce/maintain anesthesia 3. SE of benzos (2): sedation, resp dep 4. antidote to benzos is: flumazenil 5. key points of benzos (2): short -term use only, taper 6. indications for buspirone (1): anxiety (panics, OCD, PTSD) 7. difference between benzos and busprione: benzos cause sedation and are for short -term use buspirone does not cause sedation and is for long-term use 8. key points (2) of buspirone: effects take several weeks; take it with meals to avoid GI upset 9. SSRIs (5): -sertraline -fluoxetine -citalopram -escitalopram -paroxetine 10. SSRIs indications (2): anxiety and depression 11. SE of SSRIs (3): sexual dysfunction, wt gain, SEROTONIN SYNDROME 12. paroxetine SE to look for: insomnia (can't sleep --ever seen a sleepy parrot? of course not) 13. SS of serotonin syndrome: fever, sweaty, tremors 14. key point of SSRIs (4): do not take with St. John's wort stop for 2w before starting a MAOI full effects take a few weeks taper slowly 15. indications for bupropion (2): depression and smoking cessation 16. SE of bupropion (6): insomnia, wt loss, stop smoking, dec appetite, inc libido, *seizures* 17. main SE of trazodone (2): sleepy, priapism "im not done" 18. *remember* amitriptyline because...: Ami tripped in the dessert... 19. SE of amitriptyline (9): anticholinergic SE: *urinary retention*, constipation, dry mouth, blurry vision, photophobia, tachycardia Sedation, Sweating, Seizures 20. indications for amitriptyline: depression, anxiety 21. teaching for amitriptyline (4): chew gum, sunglassess, high fiber, high fluids 22. 2 MAOIs: Phenelzine Tranylcypromine 23. indications for MAOIs: depression 24. major complication of MAOIs and what causes this: *hypertensive crisis* with the ingestion of tyramine -rich foods (beer, wine, aged cheese, ripe bananas and avocados, aged meats) 25. other than tyramines, what should you avoid while on MAOIs (1): interact with many other meds (esp over the counter cold meds) 26. main drug for bipolar: lithium 27. SE of lithium (4): fine hand tremors, polyuria, wt gain, renal toxicity 28. key points of lithium (4): monitor labs!!! narrow acceptable range do not use in renal patients stop if dehydrated need adequate fluid and sodium intake 29. lab value for lithium toxicity: >1.5 mEq/L 30. SS of lithium toxicity (5): coarse tremors, confusion, low BP, seizures, tinnitus 31. 7 antiepileptic drugs: phenytoin valproate benzodiazepines gabapentin carbamazepine topiramate lamotrigine 32. indications for antiepileptics: seizures and bipolar/mood disorders 33. SE of carbamazepine (1): blood dyscrasias (low RBCs, low leukocytes, etc.) (a lot crazy cars like herby fully loaded) 34. SE of valproic acid (1): hepatotoxicity acid hurts my liver :(