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Summary SV Chemie block 2.2

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Detailed summary of the material for chemistry in block 2.2.

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Summarized whole book?
No
Which chapters are summarized?
H22, h23, h24
Uploaded on
June 18, 2016
Number of pages
7
Written in
2014/2015
Type
Summary

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Chemie
HC 1
Metabolisme = chemische reacties voor energie.
 Katabool = energie komt vrij (vertering KH)
 Anabool = energie is nodig (opbouwen van een enzym)

3 stappen:
1. Hydrolyse = van grote naar wat kleinere stukjes.
2. Verdere afbraak = bijvoorbeeld van aminozuren.
3. Via CZC (citroenzuurcyclus) wordt ATP gemaakt in mitochondrie (van acetyl-CoA naar ATP).

Acetyl-CoA (C2) + oxaalazijnzuur (C4) levert Citroenzuur (C6).

Acetyl-CoA zorgt voor energie in de citroenzuurcyclus.

Je kunt van acetyl-CoA alleen terug naar vetzuren (vetten).

ATP = adenise trifosfaat (3 fosfaatgroepen aan het einde)
ADP = difosfaat
Pi = fosfaatgroep die is afgesplitst

NAD+ = co-enzym, gereduceerd met 2 H'tjes. Dit is een H'tjes verslinder.

Oxidator = kan H'tjes opnemen.

Oxidatieve fosforylering vindt plaats in de mitochondriën.

Oxaalazijnzuur = een katalysator.

Eindproducten citroenzuurcyclus:
 NADH2 x 3 = 9 ATP
 CO2 x 2
 FADH2 x 1 = 2 ATP
 GTP x 1 = 1 ATP
 Totaal = 12 ATP


HC 2
Glucose kunnen wij omzetten in pyruvaat. Pyruvaat kan omgezet worden in acetyl-CoA.

4 manieren:
1) Glycolyse = afbraak van glucose naar pyruvaat.
2) Gluconeogenese = opbouw van pyruvaat naar glucose (vindt plaats in de lever).
3) Glycogenese = glucose omzetten in glycogeen (voor opslag).
3) Glycogenolyse = afbraak van glycogeen.

Genese = opbouw
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