IMMUNOLOGY HMX NEW EXAM GUIDE SOLUTION UPDATE 2022

dactylitis - Inflammation of an entire digit (a finger or a toe), also referred to as 'sausage digit'. Enthesitis - Inflammation of the site where a tendon or ligament inserts into a bone. Intertriginous - Referring to areas where skin rubs together, such as under the armpits and in the groin. Lymphocytes - Small leukocytes that are central players in the adaptive immune system. include T cells and B cells. Plasmacytoid dendritic cell (pDC) - A type of dendritic cell that produces large amounts of type I interferon. TNFα - A pro-inflammatory cytokine, often released by macrophages and dendritic cells early in acute inflammation. Type I interferon (type I IFN) - A class of pro-inflammatory cytokines. group of cytokines that initiate signaling that activates the antiviral state. can be produced by most cells in the body, but pDCs are very efficient at producing these cytokines. innate immune system - Exists before exposure to pathogens Capable of very rapid response Required to activate slower adaptive immune system Inflammation - delivery of cells, proteins and fluid into infected or injured tissue, defense against microbes or repair of tissue Leukocytes (WBC) - Neutrophils (polymorphonuclear leukocytes), Monocytes, Lymphocytes, Eosinophils, Basophils Tissues sentinel cells - Immune cells residing in tissues like epithelium, secrete proinflammatory cytokines. Dendritic cells, Tissue resident macrophag