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Chapter 14 practice questions metabolism and toxicology

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This document provides the practice questions on the topics of chapter 14.

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1. The kidney is responsible for all of the following EXCEPT:
- release of angiotensin.
2. Which of the following does NOT contribute to filtrate formation in the
nephron?
- positive charge of glomerular capillary wall.
3. Which of the following is NOT a characteristic of the loop of Henle?
- Water is freely permeable in the thin ascending limb.
4. The kidneys constitute 0.5% of total body mass and receive approximately how
much of the resting cardiac output?
- 20% to 25%.
5. Which of the following is most likely to occur after a toxic insult to the kidney?
- Clinical tests will likely show normal renal function.
6. Chronic renal failure does not typically result in:
- decrease in GFR of viable nephrons.
7. All of the following statements regarding toxicity to the kidney are true
EXCEPT:
- The distal convoluted tubule is the most common site of toxicant-induced
renal injury.
8. Which of the following test results is NOT correctly paired with the underlying
kidney problem?
- brush-border enzymuria—glomerulonephritis.
9. Renal cell injury is NOT commonly mediated by which of the following
mechanisms?
- increased Na + ,K+ -ATPase activity.
10. Which of the following statements is FALSE with respect to nephrotoxicants?
- Chronic consumption of NSAIDs results in nephrotoxicity that is reversible
with time.

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