W2 T3; How the brain adapts
Tolerance, withdrawal and mechanisms will be covered
Receptor recap
Target of specific drug; receptors are proteins
Located in cell surface membrane and 3d structure
Agonist binding produces cellular effects
Different types:
Metabotropic are GPCR
Types
As you go across, time scale increases; nuclear longer as changes gene transcription
Brain has about 10,000 connections on each post-synaptic neuron
Tolerance, withdrawal and mechanisms will be covered
Receptor recap
Target of specific drug; receptors are proteins
Located in cell surface membrane and 3d structure
Agonist binding produces cellular effects
Different types:
Metabotropic are GPCR
Types
As you go across, time scale increases; nuclear longer as changes gene transcription
Brain has about 10,000 connections on each post-synaptic neuron
