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Samenvatting Hart en vaten 1 - overzicht cardiologie

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Beknopt overzicht van cardiologie (welke factoren bepalen de bloeddruk) + screenshort van de belangrijkste grafieken en hormonen. Score: 18/20

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Uploaded on
November 15, 2022
File latest updated on
November 15, 2022
Number of pages
7
Written in
2021/2022
Type
Summary

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Hart en vaten 1:
overzicht bloeddruk
belangrijkste grafieken en hormonen

, BD




CO SVR CVD




Bloedvolume
Veneuze compliantie
Spierpomp
SVR (OS)
HF SV Vaattonus (constrictie) Viscositeit Veneuze vaattonus (constrictie)
CO
Expiratie en valsalva
Inspiratie
Liggen of hurken




OS ↑bloedvolume via: RAAS,
NO (via PS: ACh, Shear stress,
OS en circulerende ACh op GSC (EC dysfunctie) bradykinine) vasopressine/ADH, aldosteron
PS
catecholamines EDV ESV Myogene respons (venen) ↓bloedvolume via: ANP
GM: β-blokkers Autoreg: reactieve hyperemie
GM: atropine Endotheline, angiotensine 2, PGI2
aldosteron




Preload (voorbelasting) Afterload (nabelasting) Inotropie (contractiliteit)




OS en circulerende
Veneuze druk (zie CVD)
HF catecholamines PS
Compliantie ventrikels
Inotropie ventrikels Druk aorta/a. pulmonalis HF (Boweditch: ↑Na+ = ↑Ca2+) Systolisch falen (ischemie,
Inotropie atria
Inflow weerstand Afterload (Anrep) aritmie, cariomyopathie,...)
Outflow weerstand/afterload
GM: digitalis, PDE-I

, Frank-Starling

- = adaptatiemechanisme van het hart
- “Het hart kan binnen fysiologische grenzen eender welk volume ejecteren tegen eender welke druk door zijn EDV aan te passen”




Toename preload Toename afterload Veranderingen inotropie

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