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Erasmus Univeristy Rotterdam: The Human Body Summary (1.4) Lectures included

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Erasmus Univeristy Rotterdam Summary 1.4 The Human Body, lectures included.

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1.4 SUMMARY

PROBLEM 1
BIOLOGICAL VOCAB
 Dorsal: toward the back, ventral: toward the stomach.
 Horizontal: parallel to the horizon, sagittal: divides the body into
right and left, frontal: divides the body into dorsal and ventral.
 Anterior: toward to front end (göğüs), posterior: toward the rear
end (sırt)
 Lateral: towards side, away from midline, medial: towards
midline, away from side.
 Ipsilateral: on the same side of the body, contralateral: on the
opposite side of body.
 Clusters of cell bodies in CNS is nuclei, clusters of cell bodies in
PNS is ganglia (daha küçük ama sayıca daha fazla)
 Bundles of axons in CNS is tracts, bundles of axons in PNS is
nerves.

NEURONS

1) Axons: Myelin sheath (fatty insulation around axon) covers, myelin
sheaths protect the axon and impulse. Have specific gaps between
myelin sheaths called nodes of ranvier. They pass information to
long distances and have axon branches which passes the
information to different directions.
2) Dendrites: collection of information from other neurons, they have
branches with fibers, they have synaptic receptors. (The grater the
surface area of dendrites, more information they can receive.
3) Soma/cell body: Includes nucleus and other organelles. Location of
DNA (cell nucleus)
4) Presynaptic terminals/terminal buttons: Send neurotransmitters to
the synaptic cleft, connection with other neurons.
 Neurons do not have centrosomes so they can’t reproduce.
 Neurons have lot of mitochondria bc they require energy for
impulse transformation.
1) Sensory neurons (afferent axon-brings in the info-): Neurons
responsible for converting external stimuli from the environment to
an internal stimuli. They feel sensory output via their receptors.
(Sense external stimuli)
2) Motor neurons (efferent axon -carries info away): Mostly due
within muscles or glands. They respond to the CNS.
3) Inter neurons: Communication between sensory, motor neurons
that are in CNS. No or small axon. Integration of neural activity no
to pass on information.
 When sensory neurons are damaged: no feeling is felt. (local
anesthesia)
 Inter neurons are damaged: people feel things, unable to interpret
them. (paralysis)
 Motor neurons are damaged: feeling is felt, interpretion have been
made but one can’t control their muscles. (Pain is felt but they can’t
go away from the pain)
 Neurons cell membrane: lipid bilayer- selectively permeable.

, A neuron with more than 2 processes emanating from their cell
bodies are multipolar, only 1 process is unipolar, and 2 processes
is bipolar neuron.

GLIAL CELLS
 Remove waste material as viruses, fungi or other microorganisms,
helps neurons, support and feed neurons. Come glial cells form
myelin sheaths.

BRAIN
Consists of 3 parts. (Forebrain, midbrain and
hindbrain).
 Gryus or gyri (çıkıntı), sulcus (girinti), sulci
(pl)

Forebrain
 Consists of 2 cerebral hemispheres. (right and
left)
 Outer portion is the cerebral cortex.
Telencephalon (cerebral cortex, limbic system, basal ganglia, cerebral
commissures)

CEREBRAL CORTEX (lobes, major fissures and gyri)
 Consists of 4 lobes.
Frontal lobe
 Controls primary motor cortex (precentral gyrus: location of
primary motor cortex) (control of fine movement)
 Problem solving, thinking, planning.
 Prefrontal cortex: the very anterior portion of frontal lobe.
(organizing behavior)
Temporal lobe
 Cortical target for auditory info.
 Left temporal lobe: understanding spoken language.
 Contains hippocampus.
 Hallucinations due to tumors.
Parietal Lobe
 Has somatosensory cortex (postcentral gyrus: location of
somatosensory cortex): receives sensory information from touch
receptors and muscle stretch receptors.
 Pressure, light-touch information.
 Orientation, movement, recognition.
Occipital lobe
 Visual information.
 Contains primary visual cortex in the posterior pole.
 Damage: cortical blindness.
 Eyes provide stimuli, visual cortex provides experience. (?)
Central fissure/girinti
 Separates frontal and parietal lobe. (primary sensory cortex:
parietal lobe, primary motor cortex: frontal lobe)
Lateral fissure
 Separates the temporal lobe from the frontal and parietal lobes.
Longitudinal fissure/sulcus
 Deep grove that separates two hemispheres.

,Precentral gyrus
 Site of primary motor cortex.
Postcentral gyrus
 Location of primary somatosensory cortex.
Superior temporal gyrus
 Contains auditory cortex.
Cingulate gyrus
 Curved fold around the corpus callosum. (component of limbic
system)

LIMBIC SYSTEM (regulates motivated behavior)
Amygdala
 Respond to emotional information. (mostly fear) (4F’s: fighting,
fleeing, feeding and fornicating) (Located in temporal lobe)
Hippocampus
 Long term memory, orientation, face and language recognition.
(temporal lobe)
Fornix
 Connects hippocampus to the rest of the brain. (C SHAPE)
Cingulate cortex
 Learning, emotions and memory. (located in cingulate gyrus)
Septum
 Separates hemispheres (in the middle)

BASAL GANGLIA (learning, emotions)
Striatum
Caudate nucleus
 Control of movement, decision making. (damage: Alzheimer,
Parkinson disease)
Putamen
Globus pallidus
Nucleus accumbens
 Reward system, dopamine.


CEREBRAL COMMISSURES
Corpus callossum
 Connection between hemispheres.
Anterior commissures, posterior commissures
 Other connections between hemispheres

Diencephalon
Thalamus
 Receives sensory information and sends it to cerebral cortex.
 Olfactory information does not go to thalamus.
 Integration of information.
Hypothalamus
 Voluntary actions (eating, drinking, sleeping, mating)
 Responsible for homeostasis.
 Conveys messages to pituitary gland.
 Arcuate nucleus, interstitial nucleus, suprachiasmatic nucleus,
paraventricular nucleus, lateral nucleus.
Optic chiasm

,  The point where the optic nerves from each eye come together.
 Visual field

Pituitary gland
 Secrete hormones according to hypothalamus
Pineal gland
Nucleus basalis


Midbrain (Mesencephalon)
Tectum
 Root of the midbrain.
 Has superior colliculus (vision) and inferior colliculus (hearing).
(Both are important for sensory processing)
Tegmentum
 Under tectum.
 Substantia nigra, red nucleus: responsible for movement.
(dopamine). (sensory motor system)
 Ventral tegmental area: reward system, motivation, cognition and
drug addiction.
 Cerebral aqueduct: connects the 3rd and 4th ventricles
 Reticular formation: reflexes, consciousness, alertness.
 Periaqueductual gray: Suppresses pain

Hindbrain
 Consists of medulla, pons and cerebellum.
 Medulla, pons and midbrain forms brainstem. (beyin sapı)
 Reticular formation.
Medulla (medulla oblongata) (omurilik soğanı) (Myelencephalon)
 Controls vital reflexes through cranial nerves. (breathing, heart
rate, vomiting, salivation, coughing.)
 Damage to medulla is fatal.
 Non-voluntary functions.
Pons (Metencephalon)
 Contains nuclei for several cranial nerves.
 Axons from each half of brain is crossed to the opposite
side of the spinal cord, so left hemisphere controls the
muscles on the right side and opposite.
 Reticular formation (motor and sensory nerves pass)
 Plays role in sleep and arousal (locus coeruleus)
Cerebellum (Beyincik) (Metencephalon)
 Control of movement.
 Balance and coordination.
 Motor memory.

The Ventricles
 4 fluid filled cavities called the ventricles.
 Ventricles have cells called choroid plexus which produce
cerebrospinal fluid (CSF) a clear fluid similar to blood plasma.
 Ventricles shock absorption, protector.
 CSF fills the ventricles and the meninges membrane that surround
the brain and the spinal cord.

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