Pharmaceutical Calculations exam 2 practice QUESTIONS WITH
ANSWERS 100% CORRECT
A lotion contains 18% v/v of glycerin. What is the percentage strength of glycerin in w/v if 5
gallons of this lotion is prepared? Glycerin has a specific gravity of 1.25. Round to the tenth
place. Correct Answer: 22.5%
If 450 g of dextrose are dissolved in 750 mL of water with a resultant final volume of 1 liter,
what is the percentage strength of dextrose in the solution on a w/w basis? Round your answer to
the tenth place. Correct Answer: 37.5%
If fifty glycerin suppositories are made from the following formula, how many milliliters of
glycerin, having a specific gravity of 1.25, would be used in the preparation of 126
suppositories?
Glycerin 91 g
Sodium stearate 9 g
Purified water 5 g
Round your answer to the tenth place. Correct Answer: 183.5 mL
A 45-g tube of DESONATE gel contains 0.05% w/w desonide. Calculate the concentration of
desonide on an mg/g basis Correct Answer: 0.5 mg/g
A pharmacist receives the following prescription but does not have hydrocortisone powder on
hand. However, the pharmacist does have an injection containing 100 mg of hydrocortisone per
milliliter of injection. A search of the literature indicates that the injection has a specific gravity
of 1.1. Rx Hydrocortisone 1.5% Cold Cream qs 45 g How many milliliters of the hydrocortisone
injection would provide the correct amount of hydrocortisone? Round your answer to the tenth
place Correct Answer: 6.75 mL
A syrup is prepared by dissolving 700 g of sucrose in sufficient purified water to make 1000 mL
of syrup. Syrup has a specific gravity of 1.25. How many milliliters of water would be needed to
prepare 2 liters of syrup? Report your answer as a whole number Correct Answer: 1100 mL
Rx Potassium permanganate tablets 200 mg Dispense #80 Sig. Six tablets in enough water to
make 1,800 mL. Use as directed. What is the ratio strength (w/v) of the prepared solution?
Report your answer as a ratio (X:Y), in the following format (1:20,000) Correct Answer: 1:1500
Rx: Lactic Acid aa
Salicylic Acid 10 %
Flexible Collodion qs ad 15 mL
Sig: Apply one drop to wart twice a day.
Lactic acid is available as a liquid containing 65 g of the acid in 100 g of solution (sp.gr. 1.2).
Calculate the quantity of this solution, in milliliters, needed to fill the prescription. Round your
answer to the tenth place. Correct Answer: 1.9 mL
, If a pharmacist combined 50 mL portions of three syrups having specific gravities of 0.85, 1.25
and 1.4, what would be the specific gravity of the combined product? Round your answer to the
hundredth place Correct Answer: 1.17
The dose of gentamicin for patients with impaired renal function is adjusted to ensure
therapeutically optimal dosage. If the normal daily dose of the drug for adults is 2.5 mg/kg/day,
administered in 3 divided doses, what would be the single dose (in mg) for a patient that is 5 feet
8 inches tall, weighs 175-lb and scheduled to receive a 40% reduction of the usual dose, based on
renal impairment? Round to the nearest tenth place Correct Answer: 39.8 mg
Determine the initial maintenance dose of amikacin for a 55 year old male patient weighing 100
kg and measuring 5 ft., 9 inches in height with a serum creatinine of 2.1 mg/dL. The
maintenance dose is 5 mg/kg of ideal body weight every 8 hours. Round to the tenth place
Correct Answer: 353.5 mg
A four-agent dosage regimen, termed MOPP, for the treatment of Hodgkin's lymphoma includes
the following drugs taken over a 28-day cycle:
Mechlorethamine 6 mg/m2/day, IV, Days 1, 8
Vincristine 1.4 mg/m2/day, IV, Days 1, 8
Procarbazine 100 mg/m2/day, PO, Days 1-14
Prednisone 40 mg/m2/day, PO, Days 1-14
Calculate the total quantity (in mg) of Mechlorethamine administered over the course of the
treatment cycle for a patient that weighs 90 kg and is 5 feet 10 inches tall. Round to the tenth
place Correct Answer: 25.3 mg
The pediatric oral dose of ciprofloxacin is given is 10 to 20 mg/kg every 8 hours, not to exceed a
single dose of 400 mg irrespective of body weight. If a child weighing 55 lb is prescribed a one-
teaspoonful dose of a 6% ciprofloxacin oral suspension every 8 hours. How many milligrams of
ciprofloxacin will this child receive in a single dose? Enter your answer in the first answer blank.
__1__ Is this prescribed dose within the therapeutic range? Yes or no? Enter your answer in the
second answer blank. __2__ Correct Answer: 300 mg
yes
AURALGAN Otic Drops contains:
Antipyrine 5.4%
Benzocaine 1.4%
Acetic acid 0.01%
u-polycosanol 410 0.02 mL
Glycerin, qs ad 15 mL
(a) If a patient used 5 drops of the otic solution, equivalent to 0.25 mL, how many milligrams of
benzocaine would have been administered?
(b) What would be the ratio strength (v/v) of u-polycosanol 410? Correct Answer: 3.5 mg
1:750
ANSWERS 100% CORRECT
A lotion contains 18% v/v of glycerin. What is the percentage strength of glycerin in w/v if 5
gallons of this lotion is prepared? Glycerin has a specific gravity of 1.25. Round to the tenth
place. Correct Answer: 22.5%
If 450 g of dextrose are dissolved in 750 mL of water with a resultant final volume of 1 liter,
what is the percentage strength of dextrose in the solution on a w/w basis? Round your answer to
the tenth place. Correct Answer: 37.5%
If fifty glycerin suppositories are made from the following formula, how many milliliters of
glycerin, having a specific gravity of 1.25, would be used in the preparation of 126
suppositories?
Glycerin 91 g
Sodium stearate 9 g
Purified water 5 g
Round your answer to the tenth place. Correct Answer: 183.5 mL
A 45-g tube of DESONATE gel contains 0.05% w/w desonide. Calculate the concentration of
desonide on an mg/g basis Correct Answer: 0.5 mg/g
A pharmacist receives the following prescription but does not have hydrocortisone powder on
hand. However, the pharmacist does have an injection containing 100 mg of hydrocortisone per
milliliter of injection. A search of the literature indicates that the injection has a specific gravity
of 1.1. Rx Hydrocortisone 1.5% Cold Cream qs 45 g How many milliliters of the hydrocortisone
injection would provide the correct amount of hydrocortisone? Round your answer to the tenth
place Correct Answer: 6.75 mL
A syrup is prepared by dissolving 700 g of sucrose in sufficient purified water to make 1000 mL
of syrup. Syrup has a specific gravity of 1.25. How many milliliters of water would be needed to
prepare 2 liters of syrup? Report your answer as a whole number Correct Answer: 1100 mL
Rx Potassium permanganate tablets 200 mg Dispense #80 Sig. Six tablets in enough water to
make 1,800 mL. Use as directed. What is the ratio strength (w/v) of the prepared solution?
Report your answer as a ratio (X:Y), in the following format (1:20,000) Correct Answer: 1:1500
Rx: Lactic Acid aa
Salicylic Acid 10 %
Flexible Collodion qs ad 15 mL
Sig: Apply one drop to wart twice a day.
Lactic acid is available as a liquid containing 65 g of the acid in 100 g of solution (sp.gr. 1.2).
Calculate the quantity of this solution, in milliliters, needed to fill the prescription. Round your
answer to the tenth place. Correct Answer: 1.9 mL
, If a pharmacist combined 50 mL portions of three syrups having specific gravities of 0.85, 1.25
and 1.4, what would be the specific gravity of the combined product? Round your answer to the
hundredth place Correct Answer: 1.17
The dose of gentamicin for patients with impaired renal function is adjusted to ensure
therapeutically optimal dosage. If the normal daily dose of the drug for adults is 2.5 mg/kg/day,
administered in 3 divided doses, what would be the single dose (in mg) for a patient that is 5 feet
8 inches tall, weighs 175-lb and scheduled to receive a 40% reduction of the usual dose, based on
renal impairment? Round to the nearest tenth place Correct Answer: 39.8 mg
Determine the initial maintenance dose of amikacin for a 55 year old male patient weighing 100
kg and measuring 5 ft., 9 inches in height with a serum creatinine of 2.1 mg/dL. The
maintenance dose is 5 mg/kg of ideal body weight every 8 hours. Round to the tenth place
Correct Answer: 353.5 mg
A four-agent dosage regimen, termed MOPP, for the treatment of Hodgkin's lymphoma includes
the following drugs taken over a 28-day cycle:
Mechlorethamine 6 mg/m2/day, IV, Days 1, 8
Vincristine 1.4 mg/m2/day, IV, Days 1, 8
Procarbazine 100 mg/m2/day, PO, Days 1-14
Prednisone 40 mg/m2/day, PO, Days 1-14
Calculate the total quantity (in mg) of Mechlorethamine administered over the course of the
treatment cycle for a patient that weighs 90 kg and is 5 feet 10 inches tall. Round to the tenth
place Correct Answer: 25.3 mg
The pediatric oral dose of ciprofloxacin is given is 10 to 20 mg/kg every 8 hours, not to exceed a
single dose of 400 mg irrespective of body weight. If a child weighing 55 lb is prescribed a one-
teaspoonful dose of a 6% ciprofloxacin oral suspension every 8 hours. How many milligrams of
ciprofloxacin will this child receive in a single dose? Enter your answer in the first answer blank.
__1__ Is this prescribed dose within the therapeutic range? Yes or no? Enter your answer in the
second answer blank. __2__ Correct Answer: 300 mg
yes
AURALGAN Otic Drops contains:
Antipyrine 5.4%
Benzocaine 1.4%
Acetic acid 0.01%
u-polycosanol 410 0.02 mL
Glycerin, qs ad 15 mL
(a) If a patient used 5 drops of the otic solution, equivalent to 0.25 mL, how many milligrams of
benzocaine would have been administered?
(b) What would be the ratio strength (v/v) of u-polycosanol 410? Correct Answer: 3.5 mg
1:750
