Pharmaceutical Calculations EXAM 2022 QUESTIONS WITH
COMPLETE SOLUTIONS| VERIFIED
Mr. Jones takes 2 g of paracetamol on day 1, 0.0015 kg on day 2 and 500 mg on day 3.
How much paracetamol did Mr. Jones take, in total, over these 3 days? Give your answer in
grams. Correct Answer: 4g
Mrs. Taylor is prescribed dopamine and amoxycillin by intravenous infusion. To prepare this
infusion, you add 300 microlitres of dopamine solution and 15 mL of amoxycillin solution to 0.5
L of 0.9% w/v sodium chloride intravenous (IV) solution.
What is the total volume of mixed IV solution? Give your answer in millilitres. Correct Answer:
515.3mL
Miss Avon is prescribed dipyridamole for the prevention of stroke. The prescribed dose is 2
tablets of dipyridamole, each containing 100 mg, to be taken 3 times a day.
What is the total quantity of dipyridamole taken by the patient in 7 days? Give your answer in
grams Correct Answer: 4.2g
A cruise ship breaks down in the Bermuda Triangle with 25 passengers and 15 crewmembers
stranded on board. The ship's doctor is worried about scurvy breaking out and prescribes 100 mg
of vitamin C for each person per day. In total, they are marooned for a 365 days.
How many kilograms of vitamin C are needed for the entire 365 days? Correct Answer: 1.46kg
'Ibugel' contains 50 mg of ibuprofen per gram of gel. Each tube contains 100 g of gel.
How many kilograms of ibuprofen are needed to manufacture 2000 tubes of gel? Correct
Answer: 10kg
A salbutamol inhaler delivers 100 micrograms in each 'puff' and each inhaler contains 200 doses.
How many grams of drug are contained in the device? Correct Answer: 0.02g
Mr. Khan takes diazepam for anxiety. Each tablet contains 2 mg of the diazepam. Mr. Khan
takes 2 tablets, 3 times a day.
How many millimoles of diazepam does he take each day (RMM diazepam = 285)? Give your
answer to 1 significant figure. Correct Answer: 0.04mmol
Convert 2.5 L to cm3. Correct Answer: 2500cm3
Mr. Porter is prescribed Testogel sachets. Each sachet contains 5 g of gel with 0.06 g of a
testosterone-based compound in it. The RMM of this compound is 300.
How many millimoles of the testosterone-based compound does each 5 g sachet of gel contain?
Correct Answer: 0.2mmol
Miss Nicholson, age 5, weighs 25 kg. She undergoes surgery during which she needs an
intravenous injection of fentanyl at a dose of 3 micrograms/kg. The fentanyl injection contains
50 micrograms/mL.
What volume, in mL, of the fentanyl injection should she be given? Correct Answer: 1.5mL
, You are an industrial pharmacist involved in the manufacturing of tablets of a new anti-ulcer
drug. Each tablet contains 200 mg of the drug. The drug itself is unstable and so tablets are
manufactured using a "salt form" of the drug. The MWt of the drug is 400 and the MWt of the
salt form is 600.
How many kilograms of the salt form do you need to make 1 million tablets?
Dopamine, MWt = 153 Dopamine Hydrochloride, MWt = 190 Correct Answer: 300kg
Mr. Harris gargles with 10 mL of 0.2 % w/v chlorhexidine gluconate mouthwash twice a day, for
the management of mouth ulcers.
How many grams of chlorhexidine gluconate does Mr. Harris use each day? Correct Answer:
0.04g
Miss Sully is 6 years old and weighs 20.1 kg. She is prescribed 2 mg/5 mL diazepam oral
solution for muscle spasm at a dose of 5 mg twice a day.
What is the concentration of diazepam oral solution expressed as a ratio concentration? Correct
Answer: 1:2500
Mr. Williams is prescribed Oramorph oral solution with instructions to take 2.5 mL every 4
hours. The concentration of morphine sulfate in Oramorph solution is 10 mg/ 5 mL.
What is the millimolar concentration of morphine sulfate in Oramorph oral solution? For the
purpose of this question, you can take the RMM of morphine sulfate to be 400. Correct Answer:
5mM
Mrs. Ali takes two soluble 500 mg tablets of paracetamol dissolved in 250 mL of water, four
times a day for a headache.
What is the concentration, expressed in % w/v, of paracetamol in the resultant solution? Correct
Answer: 0.4w/v
Mr. Coach keeps normal saline sachets in the first aid kit of the rugby under 10s team for
cleaning grazes. What is the concentration in mmol/L of a 0.9% w/v sodium chloride solution?
For the purpose of this question, you can take the RMM of Sodium chloride to be 60. Correct
Answer: 150mmol/L
It is winter flu season and you are preparing for the start of the flu vaccination service in your
pharmacy. Your standard operating procedure require you to have two adrenaline auto-injectors
available in case of the rare event that a patient experiences anaphylactic shock.
The initial recommended dose of adrenaline for adults is 500 micrograms intramuscularly (into
the thigh). An "Emerade" injection provides this dose in 0.5 mL of solution. Express this as a
ratio concentration. Correct Answer: 1:1000
Mrs. Flake asks you for advice on the 400 mg potassium permanganate tablets which you have
dispensed to her. She needs to make a 0.01 % w/v solution to use as a wound wash, by dissolving
one tablet in water.
What volume, in litres, should she make her solution up to give her a 0.01 % w/v solution?
Correct Answer: 4l
COMPLETE SOLUTIONS| VERIFIED
Mr. Jones takes 2 g of paracetamol on day 1, 0.0015 kg on day 2 and 500 mg on day 3.
How much paracetamol did Mr. Jones take, in total, over these 3 days? Give your answer in
grams. Correct Answer: 4g
Mrs. Taylor is prescribed dopamine and amoxycillin by intravenous infusion. To prepare this
infusion, you add 300 microlitres of dopamine solution and 15 mL of amoxycillin solution to 0.5
L of 0.9% w/v sodium chloride intravenous (IV) solution.
What is the total volume of mixed IV solution? Give your answer in millilitres. Correct Answer:
515.3mL
Miss Avon is prescribed dipyridamole for the prevention of stroke. The prescribed dose is 2
tablets of dipyridamole, each containing 100 mg, to be taken 3 times a day.
What is the total quantity of dipyridamole taken by the patient in 7 days? Give your answer in
grams Correct Answer: 4.2g
A cruise ship breaks down in the Bermuda Triangle with 25 passengers and 15 crewmembers
stranded on board. The ship's doctor is worried about scurvy breaking out and prescribes 100 mg
of vitamin C for each person per day. In total, they are marooned for a 365 days.
How many kilograms of vitamin C are needed for the entire 365 days? Correct Answer: 1.46kg
'Ibugel' contains 50 mg of ibuprofen per gram of gel. Each tube contains 100 g of gel.
How many kilograms of ibuprofen are needed to manufacture 2000 tubes of gel? Correct
Answer: 10kg
A salbutamol inhaler delivers 100 micrograms in each 'puff' and each inhaler contains 200 doses.
How many grams of drug are contained in the device? Correct Answer: 0.02g
Mr. Khan takes diazepam for anxiety. Each tablet contains 2 mg of the diazepam. Mr. Khan
takes 2 tablets, 3 times a day.
How many millimoles of diazepam does he take each day (RMM diazepam = 285)? Give your
answer to 1 significant figure. Correct Answer: 0.04mmol
Convert 2.5 L to cm3. Correct Answer: 2500cm3
Mr. Porter is prescribed Testogel sachets. Each sachet contains 5 g of gel with 0.06 g of a
testosterone-based compound in it. The RMM of this compound is 300.
How many millimoles of the testosterone-based compound does each 5 g sachet of gel contain?
Correct Answer: 0.2mmol
Miss Nicholson, age 5, weighs 25 kg. She undergoes surgery during which she needs an
intravenous injection of fentanyl at a dose of 3 micrograms/kg. The fentanyl injection contains
50 micrograms/mL.
What volume, in mL, of the fentanyl injection should she be given? Correct Answer: 1.5mL
, You are an industrial pharmacist involved in the manufacturing of tablets of a new anti-ulcer
drug. Each tablet contains 200 mg of the drug. The drug itself is unstable and so tablets are
manufactured using a "salt form" of the drug. The MWt of the drug is 400 and the MWt of the
salt form is 600.
How many kilograms of the salt form do you need to make 1 million tablets?
Dopamine, MWt = 153 Dopamine Hydrochloride, MWt = 190 Correct Answer: 300kg
Mr. Harris gargles with 10 mL of 0.2 % w/v chlorhexidine gluconate mouthwash twice a day, for
the management of mouth ulcers.
How many grams of chlorhexidine gluconate does Mr. Harris use each day? Correct Answer:
0.04g
Miss Sully is 6 years old and weighs 20.1 kg. She is prescribed 2 mg/5 mL diazepam oral
solution for muscle spasm at a dose of 5 mg twice a day.
What is the concentration of diazepam oral solution expressed as a ratio concentration? Correct
Answer: 1:2500
Mr. Williams is prescribed Oramorph oral solution with instructions to take 2.5 mL every 4
hours. The concentration of morphine sulfate in Oramorph solution is 10 mg/ 5 mL.
What is the millimolar concentration of morphine sulfate in Oramorph oral solution? For the
purpose of this question, you can take the RMM of morphine sulfate to be 400. Correct Answer:
5mM
Mrs. Ali takes two soluble 500 mg tablets of paracetamol dissolved in 250 mL of water, four
times a day for a headache.
What is the concentration, expressed in % w/v, of paracetamol in the resultant solution? Correct
Answer: 0.4w/v
Mr. Coach keeps normal saline sachets in the first aid kit of the rugby under 10s team for
cleaning grazes. What is the concentration in mmol/L of a 0.9% w/v sodium chloride solution?
For the purpose of this question, you can take the RMM of Sodium chloride to be 60. Correct
Answer: 150mmol/L
It is winter flu season and you are preparing for the start of the flu vaccination service in your
pharmacy. Your standard operating procedure require you to have two adrenaline auto-injectors
available in case of the rare event that a patient experiences anaphylactic shock.
The initial recommended dose of adrenaline for adults is 500 micrograms intramuscularly (into
the thigh). An "Emerade" injection provides this dose in 0.5 mL of solution. Express this as a
ratio concentration. Correct Answer: 1:1000
Mrs. Flake asks you for advice on the 400 mg potassium permanganate tablets which you have
dispensed to her. She needs to make a 0.01 % w/v solution to use as a wound wash, by dissolving
one tablet in water.
What volume, in litres, should she make her solution up to give her a 0.01 % w/v solution?
Correct Answer: 4l
