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Samenvatting leerpad C gastro-enterologie farmacologie

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gastro-enterologie farmacologie leerpad C (cursus + powerpoint)

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Uploaded on
October 30, 2022
Number of pages
3
Written in
2022/2023
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Summary

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Leerpad C - gastro - enterologie
farmacologie

1. Gastro-intestinaal stelsel

1.1 Maag- en duodenumpathologie
 Ulcus pepticum en GERD (gastro‐esophageal reflux
disease)

 Doel: verhogen pH maag
o Antacida: enkel bij lichte reflux klachten
▪ Vb. HCO3 (®Rennie)
o H2‐antihistaminica
▪ Vb. Ranitidine (Zantac®)
o Proton pomp inhibitoren (PPIs)
▪ Vb. Omeprazole (®Losec), Lansoprazole (®Dakar),
Pantoprazole (Pantomed®)


Eradicatieschema Helicobacter pylori: quadruple therapy

 Tweemaal per dag gedurende 10 dagen: een PPI (esomeprazol 20
mg, lansoprazol 30 mg, omeprazol 20 mg, pantoprazol 40 mg of
rabeprazol 20 mg) vóór de maaltijd
 + amoxicilline 1 g
 + metronidazol 500 mg
 + clarithromycine 500 mg

1.2 Spasmolytica
 Doel relaxatie gladde spiercel
 Directe werking
o Vb. Alverine (®Spasmine), mebeverine
o Prikkelbaredarmsyndroom
 Indirecte werking: anticholinergica
o Vb. ®Buscopan
o Koliekpijnen
o Anticholinerge nevenwerkingen: droge mond,
visusstoornissen, constipatie, …
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