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Samenvatting boek 4 farmacologie geneeskunde

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Volledige samenvatting farmacologie 3e bachelor geneeskunde boek 4. Met lesnotities. Met glans geslaagd in eerste zit.

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Uploaded on
September 16, 2022
Number of pages
47
Written in
2021/2022
Type
Summary

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Deel 4 :
Geneesmiddelen ivm het cardiovasculair stelsel

,
,
,1. Diuretica

urinevolume î ,
nettoverlies v. solutes / 1-1204
-

alle diuretica behalve , spironolactone bereiken ,
de lvminale transport locaties via de

tvbvlaire vloeistof (filtratie te secretie)

alle diuretica , behalve osmot diuretica door de PT
worden actief gesecreteerd
-
.


,




Netron




ËË;÷÷Ä
in terstitium




::
§ DT




<T
T ami loriae -10
osmotische diuretica

al dos -




terone

spirondactone #
00 urine




Algemene opmerkingen diuretica
'
s innemen
morgens
-




indicaties voor
gn zwangerschapSHT 2 Oedeem
-




-




k Combin met andere farmaca →
k ionen stoornissen
-




bij acute toediening
/ starten onderhoudstherapie →
controle met
ionogram
1 is diuretica thiol id en samen actiever ookal hebben
soms zijn apart weinig effect
-

✗ ze
,




controle vocht
goede ✗ ionen
- •

, 1.1 . Kodzuuranhudrase inhibitoren
1.1.1 .




Werking

interstitivm.tt
Lumen




-§ij
"
Hoi-↓
I
Hzld } JA # 12h03
-




↓ CA CA ↑
(021-1-120 > Wat H2O




CA : Sleutelrol in absorptie van Na HW }

vooral thv lvminale membraan in PT

pH lumen ( d Urine ) ↑


CA -

I : ⊖ CA →
minder HCOJ Van lumen naar uiterst itivm - ☐
minder Hro nr interstitivm

pH systemisch
&

Syst acidose bij langdurig gebruik
.




efficiëntie neemt na enkele dagen duidelijk af


1.1.2 .
Product :
Delete201 amide


1. 1.3 .
Farma Colline tien

per oraal
-




-
effect na 30m , Max Nadu ,
werkt 124

dosis bij
aanpassing
-
NF




1.1.4 . Klinisch
gebruik
-
sulfonamide derivaten

open hoeve glaucoom productie ↓
oogvocht
-
:




-




alualinisatie vd urine

diuretica
metabole
alualosetgv gebruik voor HF
-




-

Mountain sicnness : ↓
productie te
pH ↓ Vh ( SF



1.1.5 .
Toxiciteit
-




bijwerkingen tgv alualinisatie Urine ✗ metabole acidose
-




verergeren met / resp . acidose

-
nierstenen

-

hypokt

-
meer ammoniak in systeem circ .



encefalopathie
↳ C1 : lever pathol .




hoge dosissen
slaperigheid in
pares the sieën
-
:

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