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SGLT2 INHIBITORS AADE QUESTIONS AND ANSWERS 2022

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SGLT2 INHIBITORS AADE QUESTIONS AND ANSWERS 2022 What are the generic and trade names for SGLT2 inhibitors? - Correct Answer- They all end in flozin. Canagliflozen is Invokana. Dapa is Farxiga. Empa is Jardiance. How does glucose reabsorption work in people without diabetes? - Correct AnswerAll glucose is reabsorbed by the kidneys. No glucose is excreted in the urine. SGLT2 manages glucose reabsorption. What happens with glucose reabsorption in diabetes? - Correct AnswerHyperglycemia exceeds SGLT2 capacity to filter glucose into the urine, so excess glucose goes back into the blood. How do SGLP2 inhibitors work? - Correct Answer- Works in the kidneys in the proximal tubule. SGLT2 inhibitors block reabsorption of glucose back into the blood and causes excess glucose to go into urine. You pee out sugar. How much do SGLT2 inhibitors lower A1c? - Correct Answer- 0.5-1.0 % Do not use Dapa if GFR is less than what? - Correct Answer- 60. Do not use Cana or Empa if GFR is less than what? - Correct Answer- 45. Do SGLT2 inhibitors increase insulin secretion? - Correct Answer- No. What is the recommended dose for Cana if GFR is less than 60? - Correct Answer100 m......

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